Abstract
Adiponectin and its receptors, AdipoR1 and AdipoR2, regulate glucose and fatty acid metabolism via activation of AMP-activated protein kinase. Recent work in Nature (Iwabu et al., 2010) demonstrates that adiponectin induces a marked Ca2+ influx in skeletal muscle via AdipoR1 to control mitochondrial biogenesis, reduce oxidative stress, and enhance endurance capacity.
Original language | English |
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Pages (from-to) | 447-449 |
Number of pages | 3 |
Journal | Cell Metabolism |
Volume | 11 |
Issue number | 6 |
DOIs | |
Publication status | Published - 9 Jun 2010 |
Externally published | Yes |