Adenosine receptor ligands with oxygenated N6-substituents

Sally A. Hutchinson, Stephen P. Baker, Peter J. Scammells

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A number of novel adenosine analogs bearing oxygenated substituents in the N6-position have been prepared and evaluated as A1 adenosine agonists. Improved conditions for the synthesis of N6-substituted adenosines and a new one pot procedure for the synthesis of 2-amino-7-oxabicyclo[2.2.1]hept-5-ene are also reported.
Original languageEnglish
Pages (from-to)933-936
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Issue number7
Publication statusPublished - 5 Apr 1999

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