Additive-free clicking for polymer functionalization and coupling by tetrazine-norbornene chemistry

Claire F. Hansell, Pieter Espeel, Milan M. Stamenović, Ian A. Barker, Andrew P. Dove, Filip E. Du Prez, Rachel K. Oreilly

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140 Citations (Scopus)


Herein we report the use of a tetrazine-norbornene inverse electron demand Diels-Alder conjugation applied to polymer end-functionalization and polymer-polymer coupling. The reaction was found to be applicable to polymer-polymer coupling, as judged by SEC, DOSY NMR, and LCxSEC analyses, giving diblock copolymers by merely mixing the constituent homopolymers together under ambient conditions, using no catalyst, additive, or external stimulus.

Original languageEnglish
Pages (from-to)13828-13831
Number of pages4
JournalJournal of the American Chemical Society
Issue number35
Publication statusPublished - 7 Sep 2011
Externally publishedYes

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