Adding data to gut feelings

Benjamin J. Marsland; Nicola L. Harris

doi:10.1016/j.cell.2022.10.002

Adding data to gut feelings

Benjamin J. Marsland, Nicola L. Harris

Immunology Alfred Hospital

Research output: Contribution to journal › Comment / Debate › Other › peer-review

Abstract

Pain-sensing neurons detect environmental insults and tissue injury, driving avoidance behavior and the local release of neuropeptides. Two related papers in this issue of Cell report that gut-innervating pain neurons sense bacterial presence to both shape the constituents of the gut microbiome and protect against excessive inflammation.

Original language	English
Pages (from-to)	4046-4048
Number of pages	3
Journal	Cell
Volume	185
Issue number	22
DOIs	https://doi.org/10.1016/j.cell.2022.10.002
Publication status	Published - 27 Oct 2022

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10.1016/j.cell.2022.10.002

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title = "Adding data to gut feelings",

abstract = "Pain-sensing neurons detect environmental insults and tissue injury, driving avoidance behavior and the local release of neuropeptides. Two related papers in this issue of Cell report that gut-innervating pain neurons sense bacterial presence to both shape the constituents of the gut microbiome and protect against excessive inflammation.",

author = "Marsland, {Benjamin J.} and Harris, {Nicola L.}",

note = "Funding Information: N.L.H. is supported by a National Health and Medical Research Council ( NHMRC ) of Australia SRF-B fellowship ( #1140313 ). B.J.M. is supported by a National Health and Medical Research Council ( NHMRC ) of Australia SRF-B fellowship ( #1154344 ). We thank Matthew Macowan for support with the figure. Image was generated using BioRender. Publisher Copyright: {\textcopyright} 2022",

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N1 - Funding Information: N.L.H. is supported by a National Health and Medical Research Council ( NHMRC ) of Australia SRF-B fellowship ( #1140313 ). B.J.M. is supported by a National Health and Medical Research Council ( NHMRC ) of Australia SRF-B fellowship ( #1154344 ). We thank Matthew Macowan for support with the figure. Image was generated using BioRender. Publisher Copyright: © 2022

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N2 - Pain-sensing neurons detect environmental insults and tissue injury, driving avoidance behavior and the local release of neuropeptides. Two related papers in this issue of Cell report that gut-innervating pain neurons sense bacterial presence to both shape the constituents of the gut microbiome and protect against excessive inflammation.

AB - Pain-sensing neurons detect environmental insults and tissue injury, driving avoidance behavior and the local release of neuropeptides. Two related papers in this issue of Cell report that gut-innervating pain neurons sense bacterial presence to both shape the constituents of the gut microbiome and protect against excessive inflammation.

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Adding data to gut feelings

Abstract

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Harnessing the microbiome to protect against chronic lung diseases

Type 2 immunity: a regulator of physiology, tissue repair and metabolism

Cite this

Adding data to gut feelings

Abstract

Access to Document

Other files and links

Projects

Harnessing the microbiome to protect against chronic lung diseases

Type 2 immunity: a regulator of physiology, tissue repair and metabolism

Cite this