TY - JOUR
T1 - Adaptive transformer modelling of density function for nonparametric survival analysis
AU - Zhang, Xin
AU - Mehta, Deval
AU - Hu, Yanan
AU - Zhu, Chao
AU - Darby, David
AU - Yu, Zhen
AU - Merlo, Daniel
AU - Gresle, Melissa
AU - van der Walt, Anneke
AU - Butzkueven, Helmut
AU - Ge, Zongyuan
N1 - Publisher Copyright:
© The Author(s) 2025.
PY - 2025/1/27
Y1 - 2025/1/27
N2 - Survival analysis holds a crucial role across diverse disciplines, such as economics, engineering and healthcare. It empowers researchers to analyze both time-invariant and time-varying data, encompassing phenomena like customer churn, material degradation and various medical outcomes. Given the complexity and heterogeneity of such data, recent endeavors have demonstrated successful integration of deep learning methodologies to address limitations in conventional statistical approaches. However, current methods typically involve cluttered probability distribution function (PDF), have lower sensitivity in censoring prediction, only model static datasets, or only rely on recurrent neural networks for dynamic modelling. In this paper, we propose a novel survival regression method capable of producing high-quality unimodal PDFs without any prior distribution assumption, by optimizing novel Margin-Mean-Variance loss and leveraging the flexibility of Transformer to handle both temporal and non-temporal data, coined UniSurv. Extensive experiments on several datasets demonstrate that UniSurv places a significantly higher emphasis on censoring compared to other methods.
AB - Survival analysis holds a crucial role across diverse disciplines, such as economics, engineering and healthcare. It empowers researchers to analyze both time-invariant and time-varying data, encompassing phenomena like customer churn, material degradation and various medical outcomes. Given the complexity and heterogeneity of such data, recent endeavors have demonstrated successful integration of deep learning methodologies to address limitations in conventional statistical approaches. However, current methods typically involve cluttered probability distribution function (PDF), have lower sensitivity in censoring prediction, only model static datasets, or only rely on recurrent neural networks for dynamic modelling. In this paper, we propose a novel survival regression method capable of producing high-quality unimodal PDFs without any prior distribution assumption, by optimizing novel Margin-Mean-Variance loss and leveraging the flexibility of Transformer to handle both temporal and non-temporal data, coined UniSurv. Extensive experiments on several datasets demonstrate that UniSurv places a significantly higher emphasis on censoring compared to other methods.
KW - Deep learning
KW - Margin-Mean-Variance loss
KW - Survival analysis
KW - Transformer
UR - http://www.scopus.com/inward/record.url?scp=85217782687&partnerID=8YFLogxK
U2 - 10.1007/s10994-024-06686-w
DO - 10.1007/s10994-024-06686-w
M3 - Article
AN - SCOPUS:85217782687
SN - 0885-6125
VL - 114
JO - Machine Learning
JF - Machine Learning
IS - 2
M1 - 31
ER -