Adaptation of pandemic H2N2 influenza A viruses in humans

CEIRS H2N2 Working Group

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Abstract

The 1957 A/H2N2 influenza virus caused an estimated 2 million fatalities during the pandemic. Since viruses of the H2 subtype continue to infect avian species and pigs, the threat of reintroduction into humans remains. To determine factors involved in the zoonotic origin of the 1957 pandemic, we performed analyses on genetic sequences of 175 newly sequenced human and avian H2N2 virus isolates and all publicly available influenza virus genomes.

Original languageEnglish
Pages (from-to)2442-2447
Number of pages6
JournalJournal of Virology
Volume89
Issue number4
DOIs
Publication statusPublished - Feb 2015
Externally publishedYes

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