Abstract
Endogenous toxins accumulate in blood as a result of many biochemical processes. If their concentration exceeds certain levels, they cause illness. Some toxins are volatile (e.g. CO 2 , ketones) and can be excreted by the lungs through ventilation; others are lipophilic (e.g. bile acids, bilirubin) and can be excreted by the liver via the biliary system; yet others are water soluble and non-volatile and are excreted by the kidneys. When the kidneys suffer acute failure, removal of such water-soluble toxins requires acute artificial renal replacement therapy (RRT).
Original language | English |
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Pages (from-to) | 30-37 |
Number of pages | 8 |
Journal | International Journal of Intensive Care |
Volume | 12 |
Issue number | 1 |
Publication status | Published - 1 Mar 2005 |
Externally published | Yes |