Acute kidney injury after cardiac arrest

Research output: Contribution to journalArticleResearchpeer-review


AIM: Cardiac arrest (CA) in humans causes warm renal ischemia-reperfusion injury, similar to animal models of ischemic acute kidney injury (AKI). We aimed to investigate the incidence and risk associations of AKI after CA, with or without post-resuscitation cardiogenic shock (PRCS). METHODS: We examined the renal outcomes of adult patients admitted to the intensive care unit (ICU), who survived for more than 48 h following successful resuscitation after CA. RESULTS: Of 105 patients (median age 65 years; 69% male), 58 (55.2%) had PRCS and were on vasoactive drugs beyond 24h; and 9 (8.6%) (all of whom had PRCS) received renal replacement therapy. Only 3 (6.4%) of 47 patients without PRCS had RIFLE-'I'/'F' AKI, compared to 30 (51.7%) of 58 patients with PRCS (p
Original languageEnglish
Pages (from-to)721-727
Number of pages7
Issue number6
Publication statusPublished - 2012


  • Acute Kidney Injury/diagnosis/*etiology Aged Blood Circulation Cardiopulmonary Resuscitation Creatinine/blood Female Heart Arrest/*complications/physiopathology/therapy Humans Male Middle Aged Reperfusion Injury/*etiology Shock, Cardiogenic/etiology

Cite this