TY - JOUR
T1 - Acute incremental exercise to maximal performance does not cause alterations in serum oxidant levels of healthy young individuals
AU - Amir, O.
AU - Yamin, C.
AU - Sagiv, M.
AU - Eynon, N.
AU - Shnizer, S.
AU - Kagan, T.
AU - Reznick, A. Z.
AU - Sagiv, M.
AU - Amir, R. E.
PY - 2009/3
Y1 - 2009/3
N2 - Aim. This study was designed to analyze serum oxidative stress (OS) levels in healthy young individuals performing a routine maximal aerobic exercise and to evaluate the correlation between OS levels and physiological parameters. Methods. Serum OS levels were studied by thermochemilumi-nescence (TCL) parameters at rest and following maximal aerobic exercise in 85 healthy young subjects. Levels were mea-sured by a real time on line TCL assay (higher TCL-Ratio and TCL-H3 = lower OS level). Results. Aerobic capacity had no effect on baseline OS levels. Post-exercise OS levels correlated with maximal oxygen uptake (V̇O2max) (P<0.005), delta V̇O2 (V̇O2max- V̇O2rest) (P<0.005), anaerobic threshold (VTH) (P<0.01), and total oxygen uptake (especially O2 after VTH), (P<0.005). TCL-Ratio was related to total running time (P<0.01), as well. Post-exercise OS levels for the whole study group did not vary from baseline values. However, individuals with higher fitness level (V̇O2max >per-centile 60) had significantly lower values of TCL-H3 (P=0.04) and tended to have lower TCL-Ratio, indicating they had ele-vated OS levels. In a multivariate analysis OS level was most affected by V̇O2 after VTH (anaerobic phase of the test) (P=0.003; adjusted odds ratio of 3.41,95% confidence interval: 1.55-7.48). Conclusion. In conclusion, acute incremental exercise to maxi-mal performance does not cause alterations in serum oxidant levels of healthy young individuals. In healthy individuals performing maximal aerobic exercise, OS levels correlate with maximal aerobic power.
AB - Aim. This study was designed to analyze serum oxidative stress (OS) levels in healthy young individuals performing a routine maximal aerobic exercise and to evaluate the correlation between OS levels and physiological parameters. Methods. Serum OS levels were studied by thermochemilumi-nescence (TCL) parameters at rest and following maximal aerobic exercise in 85 healthy young subjects. Levels were mea-sured by a real time on line TCL assay (higher TCL-Ratio and TCL-H3 = lower OS level). Results. Aerobic capacity had no effect on baseline OS levels. Post-exercise OS levels correlated with maximal oxygen uptake (V̇O2max) (P<0.005), delta V̇O2 (V̇O2max- V̇O2rest) (P<0.005), anaerobic threshold (VTH) (P<0.01), and total oxygen uptake (especially O2 after VTH), (P<0.005). TCL-Ratio was related to total running time (P<0.01), as well. Post-exercise OS levels for the whole study group did not vary from baseline values. However, individuals with higher fitness level (V̇O2max >per-centile 60) had significantly lower values of TCL-H3 (P=0.04) and tended to have lower TCL-Ratio, indicating they had ele-vated OS levels. In a multivariate analysis OS level was most affected by V̇O2 after VTH (anaerobic phase of the test) (P=0.003; adjusted odds ratio of 3.41,95% confidence interval: 1.55-7.48). Conclusion. In conclusion, acute incremental exercise to maxi-mal performance does not cause alterations in serum oxidant levels of healthy young individuals. In healthy individuals performing maximal aerobic exercise, OS levels correlate with maximal aerobic power.
KW - Chemiluminescent measurements
KW - Exercise
KW - Free radicals
KW - Oxygen consumption
KW - Reactive oxygen species
UR - http://www.scopus.com/inward/record.url?scp=67649095743&partnerID=8YFLogxK
M3 - Article
C2 - 19188903
AN - SCOPUS:67649095743
SN - 0022-4707
VL - 49
SP - 105
EP - 111
JO - The Journal of Sports Medicine and Physical Fitness
JF - The Journal of Sports Medicine and Physical Fitness
IS - 1
ER -