Activities of colistin- and minocycline-based combinations against extensive drug resistant acinetobacter baumannii isolates from intensive care unit patients

Wang Liang; Xiao-Fang Liu; Jun Huang; De-mei Zhu; Jian Li; Jing Zhang

doi:10.1186/1471-2334-11-109

Activities of colistin- and minocycline-based combinations against extensive drug resistant acinetobacter baumannii isolates from intensive care unit patients

Wang Liang, Xiao-Fang Liu, Jun Huang, De-mei Zhu, Jian Li, Jing Zhang

Drug Delivery Disposition & Dynamics

Research output: Contribution to journal › Article › Research › peer-review

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Abstract

Extensive drug resistance of Acinetobacter baumannii is a serious problem in the clinical setting. It is therefore important to find active antibiotic combinations that could be effective in the treatment of infections caused by this problematic superbug . In this study, we analyzed the in vitro activities of three colistin-based combinations and a minocycline-based combination against clinically isolated extensive drug resistant Acinetobacter baumannii (XDR-AB) strains.

Original language	English
Pages (from-to)	e1 - e7
Number of pages	7
Journal	BMC Infectious Diseases
Volume	11
Issue number	109
DOIs	https://doi.org/10.1186/1471-2334-11-109
Publication status	Published - 2011

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10.1186/1471-2334-11-109

Cite this

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title = "Activities of colistin- and minocycline-based combinations against extensive drug resistant acinetobacter baumannii isolates from intensive care unit patients",

abstract = "Extensive drug resistance of Acinetobacter baumannii is a serious problem in the clinical setting. It is therefore important to find active antibiotic combinations that could be effective in the treatment of infections caused by this problematic superbug . In this study, we analyzed the in vitro activities of three colistin-based combinations and a minocycline-based combination against clinically isolated extensive drug resistant Acinetobacter baumannii (XDR-AB) strains.",

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AU - Liang, Wang

AU - Liu, Xiao-Fang

AU - Huang, Jun

AU - Zhu, De-mei

AU - Li, Jian

AU - Zhang, Jing

PY - 2011

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N2 - Extensive drug resistance of Acinetobacter baumannii is a serious problem in the clinical setting. It is therefore important to find active antibiotic combinations that could be effective in the treatment of infections caused by this problematic superbug . In this study, we analyzed the in vitro activities of three colistin-based combinations and a minocycline-based combination against clinically isolated extensive drug resistant Acinetobacter baumannii (XDR-AB) strains.

AB - Extensive drug resistance of Acinetobacter baumannii is a serious problem in the clinical setting. It is therefore important to find active antibiotic combinations that could be effective in the treatment of infections caused by this problematic superbug . In this study, we analyzed the in vitro activities of three colistin-based combinations and a minocycline-based combination against clinically isolated extensive drug resistant Acinetobacter baumannii (XDR-AB) strains.

U2 - 10.1186/1471-2334-11-109

DO - 10.1186/1471-2334-11-109

M3 - Article

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VL - 11

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JO - BMC Infectious Diseases

JF - BMC Infectious Diseases

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