Activins in male reproduction

Research output: Chapter in Book/Report/Conference proceedingEncyclopaedia / Dictionary EntryOtherpeer-review

Abstract

The activins are growth factors in the transforming growth factor-β (TGFβ) superfamily. They have both endocrine and paracrine roles that are central to male reproductive biology and health. This article gives a general overview of activin structure and signaling activity. Activin action within the pituitary is described in the context of the hypothalamic–pituitary–gonadal axis of the male. Activin intratesticular actions affecting cell fate and organ growth are identified, including distinctions between somatic and germline functions and developmentally regulated effects. Areas where dysregulated activin function may be of relevance to male reproductive pathologies are considered, including infertility, inflammation, and testicular cancer.
Original languageEnglish
Title of host publicationEncyclopedia of Reproduction
Subtitle of host publicationVolume 1: Male Reproduction
EditorsMichael K. Skinner
Place of PublicationOxford UK
PublisherAcademic Press
Pages208-214
Number of pages7
Volume1
Edition2nd
ISBN (Electronic)9780128151457
ISBN (Print)9780128118993
DOIs
Publication statusPublished - 27 Jul 2018

Cite this

Loveland, K. A. L. (2018). Activins in male reproduction. In M. K. Skinner (Ed.), Encyclopedia of Reproduction: Volume 1: Male Reproduction (2nd ed., Vol. 1, pp. 208-214). Oxford UK: Academic Press. https://doi.org/10.1016/B978-0-12-801238-3.64581-6
Loveland, Katherine Ann Lakoski. / Activins in male reproduction. Encyclopedia of Reproduction: Volume 1: Male Reproduction. editor / Michael K. Skinner. Vol. 1 2nd. ed. Oxford UK : Academic Press, 2018. pp. 208-214
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Loveland, KAL 2018, Activins in male reproduction. in MK Skinner (ed.), Encyclopedia of Reproduction: Volume 1: Male Reproduction. 2nd edn, vol. 1, Academic Press, Oxford UK, pp. 208-214. https://doi.org/10.1016/B978-0-12-801238-3.64581-6

Activins in male reproduction. / Loveland, Katherine Ann Lakoski.

Encyclopedia of Reproduction: Volume 1: Male Reproduction. ed. / Michael K. Skinner. Vol. 1 2nd. ed. Oxford UK : Academic Press, 2018. p. 208-214.

Research output: Chapter in Book/Report/Conference proceedingEncyclopaedia / Dictionary EntryOtherpeer-review

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Loveland KAL. Activins in male reproduction. In Skinner MK, editor, Encyclopedia of Reproduction: Volume 1: Male Reproduction. 2nd ed. Vol. 1. Oxford UK: Academic Press. 2018. p. 208-214 https://doi.org/10.1016/B978-0-12-801238-3.64581-6