Activin and related proteins in inflammation: Not just interested bystanders

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Abstract

Activin A, a member of the transforming growth factor-? superfamily, is released rapidly into the circulation during inflammation. This review examines the evidence that activin is a critical mediator of inflammation and immunity. Activin modulates several aspects of the inflammatory response, including release of pro-inflammatory cytokines, nitric oxide production and immune cell activity.
Original languageEnglish
Pages (from-to)153 - 164
Number of pages12
JournalCytokine and Growth Factor Reviews
Volume20
Issue number2
DOIs
Publication statusPublished - 2009

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