Activin A efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed

Amanda B McLean; Kevin A D'Amour; Karen Louise Jones; Malini Krishnamoorthy; Michael J Kulik; David M Reynolds; Alan M Sheppard; Huiqing Liu; Ying Xu; Emmanuel E Baetge; Stephen Dalton

doi:10.1634/stemcells.2006-0219

Activin A efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed

Amanda B McLean, Kevin A D'Amour, Karen Louise Jones, Malini Krishnamoorthy, Michael J Kulik, David M Reynolds, Alan M Sheppard, Huiqing Liu, Ying Xu, Emmanuel E Baetge, Stephen Dalton

Research output: Contribution to journal › Article › Research › peer-review

370 Citations (Scopus)

Original language	English
Pages (from-to)	29 - 38
Number of pages	10
Journal	Stem Cells
Volume	25
Issue number	1
DOIs	https://doi.org/10.1634/stemcells.2006-0219
Publication status	Published - 2007
Externally published	Yes

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McLean, A. B., D'Amour, K. A., Jones, K. L., Krishnamoorthy, M., Kulik, M. J., Reynolds, D. M., Sheppard, A. M., Liu, H., Xu, Y., Baetge, E. E., & Dalton, S. (2007). Activin A efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed. Stem Cells, 25(1), 29 - 38. https://doi.org/10.1634/stemcells.2006-0219

McLean, Amanda B ; D'Amour, Kevin A ; Jones, Karen Louise ; Krishnamoorthy, Malini ; Kulik, Michael J ; Reynolds, David M ; Sheppard, Alan M ; Liu, Huiqing ; Xu, Ying ; Baetge, Emmanuel E ; Dalton, Stephen. / Activin A efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed. In: Stem Cells. 2007 ; Vol. 25, No. 1. pp. 29 - 38.

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title = "Activin A efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed",

author = "McLean, {Amanda B} and D'Amour, {Kevin A} and Jones, {Karen Louise} and Malini Krishnamoorthy and Kulik, {Michael J} and Reynolds, {David M} and Sheppard, {Alan M} and Huiqing Liu and Ying Xu and Baetge, {Emmanuel E} and Stephen Dalton",

year = "2007",

doi = "10.1634/stemcells.2006-0219",

language = "English",

volume = "25",

pages = "29 -- 38",

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McLean, AB, D'Amour, KA, Jones, KL, Krishnamoorthy, M, Kulik, MJ, Reynolds, DM, Sheppard, AM, Liu, H, Xu, Y, Baetge, EE & Dalton, S 2007, 'Activin A efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed', Stem Cells, vol. 25, no. 1, pp. 29 - 38. https://doi.org/10.1634/stemcells.2006-0219

Activin A efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed. / McLean, Amanda B; D'Amour, Kevin A; Jones, Karen Louise; Krishnamoorthy, Malini; Kulik, Michael J; Reynolds, David M; Sheppard, Alan M; Liu, Huiqing; Xu, Ying; Baetge, Emmanuel E; Dalton, Stephen.

In: Stem Cells, Vol. 25, No. 1, 2007, p. 29 - 38.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Activin A efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed

AU - McLean, Amanda B

AU - D'Amour, Kevin A

AU - Jones, Karen Louise

AU - Krishnamoorthy, Malini

AU - Kulik, Michael J

AU - Reynolds, David M

AU - Sheppard, Alan M

AU - Liu, Huiqing

AU - Xu, Ying

AU - Baetge, Emmanuel E

AU - Dalton, Stephen

PY - 2007

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UR - http://www3.interscience.wiley.com/cgi-bin/fulltext/121586720/PDFSTART

U2 - 10.1634/stemcells.2006-0219

DO - 10.1634/stemcells.2006-0219

M3 - Article

VL - 25

SP - 29

EP - 38

JO - Stem Cells

JF - Stem Cells

SN - 1066-5099

IS - 1

ER -

Activin A efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed

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