TY - JOUR
T1 - Active surveillance for multidrug-resistant Gram-negative bacteria in the intensive care unit
AU - Abbott, Iain J
AU - Jenney, Adam W
AU - Spelman, Denis W
AU - Pilcher, David V
AU - Sidjabat, Hanna E
AU - Richardson, Leisha J
AU - Paterson, David L
AU - Peleg, Anton Y
PY - 2015
Y1 - 2015
N2 - A short-term program of performing serial active screening cultures (ASC) in the intensive care unit was instituted to establish a method for the detection of antibiotic-resistant Gram-negative bacteria (GNB) and the local rates of colonisation. Of all submitted ASC, 25.9 (30/116 collected swabs) isolated an antibiotic-resistant GNB. ChromID ESBL agar (bioMerieux, France) identified the majority of these organisms, with the additional antibiotic-impregnated media [MacConkey agar (MCA) with ciprofloxacin, MCA with gentamicin and MCA with ceftazidime] adding limited benefit. Compared to swabs performed on admission, 37.8 (14/37) of patients cultured a new antibiotic-resistant isolate on discharge. Serial screening in intensive care has the ability to identify patients with unrecognised colonisation with antibiotic-resistant GNB; however, the increase in the laboratory workload and logistical challenges in the collection of the surveillance swabs may limit this program s expansion.
AB - A short-term program of performing serial active screening cultures (ASC) in the intensive care unit was instituted to establish a method for the detection of antibiotic-resistant Gram-negative bacteria (GNB) and the local rates of colonisation. Of all submitted ASC, 25.9 (30/116 collected swabs) isolated an antibiotic-resistant GNB. ChromID ESBL agar (bioMerieux, France) identified the majority of these organisms, with the additional antibiotic-impregnated media [MacConkey agar (MCA) with ciprofloxacin, MCA with gentamicin and MCA with ceftazidime] adding limited benefit. Compared to swabs performed on admission, 37.8 (14/37) of patients cultured a new antibiotic-resistant isolate on discharge. Serial screening in intensive care has the ability to identify patients with unrecognised colonisation with antibiotic-resistant GNB; however, the increase in the laboratory workload and logistical challenges in the collection of the surveillance swabs may limit this program s expansion.
UR - http://journals.lww.com/pathologyrcpa/Abstract/2015/10000/Active_surveillance_for_multidrug_resistant.12.aspx
U2 - 10.1097/PAT.0000000000000302
DO - 10.1097/PAT.0000000000000302
M3 - Article
SN - 0031-3025
VL - 47
SP - 575
EP - 579
JO - Pathology
JF - Pathology
IS - 6
ER -