Action potential heterogeneity assists frequency entrainment in the intact cardiac pacemaker

SL Cloherty, NH Lovell, S Dokos, BG Celler

Research output: Chapter in Book/Report/Conference proceedingConference PaperOtherpeer-review

Abstract

The role of cellular heterogeneity in frequency entrainment of the primary cardiac pacemaker has been investigated using an idealized two dimensional model of the rabbit sinoatrial node and surrounding atrial tissue. Simulation results are presented which support the hypothesis, that regional variation in action potential waveshape contributes to pacemaker synchronization in-vivo.
Original languageEnglish
Title of host publicationSecond Joint EMBS-BMES Conference 2002, Vols 1-3, Conference Proceedings: Bioengineering - Integrative Methodologies, New Technologies
Pages248-249
Number of pages2
Publication statusPublished - 2002
Externally publishedYes
EventInternational Conference of the IEEE Engineering in Medicine and Biology Society 2002 - Houston, United States of America
Duration: 23 Oct 200226 Oct 2002
Conference number: 24th

Conference

ConferenceInternational Conference of the IEEE Engineering in Medicine and Biology Society 2002
Abbreviated titleEMBC 2002
CountryUnited States of America
CityHouston
Period23/10/0226/10/02

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