ACTH producing pulmonary carcinoid and pituitary macroadenoma: A fortuitous association?

Ming Wong, S. H. Isa, N. A. Kamaruddin, B. A.K. Khalid

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3 Citations (Scopus)

Abstract

We report a case of a 45 year-old man who presented initially with a non-functioning pituitary macroadenoma. A routine chest radiography done preoperatively revealed a right lung nodule which was confirmed by computed tomography (CT) of the thorax. Transfrental hypophysectomy was performed while a conservative approach was taken for the lung nodule. Four years later, he presented acutely with adrenocorticotropic hormone (ACTH) dependent Cushing's syndrome which resolved following a right lobectomy. Histological examination revealed an atypical carcinoid. To our knowledge, this is the first reported case of an ectopic ACTH secreting pulmonary carcinoid found in association with a non-functioning pituitary macroadenoma.

Original languageEnglish
Pages (from-to)168-170
Number of pages3
JournalMedical Journal of Malaysia
Volume62
Issue number2
Publication statusPublished - Jun 2007
Externally publishedYes

Keywords

  • ACTH syndrome
  • Carcinoid tumour
  • Cushing's syndrome
  • Ectopic
  • Multiple endocrine neoplasia
  • Pituitary neoplasms

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