TCR-pMHC recognition – through the looking glass.
The image shows a brightly colored canonical interaction between TCR and pMHC which is conducive to signal transduction. The faded mirror image shows a reversed TCR-pMHC interaction which is unable to support signal transduction and thus T cell activation. (Created by Dr. Erica Tandori, Rossjohn lab)
Read the full paper in Science titled: Canonical T cell Receptor Docking on peptide-MHC is essential for T cell signaling.
|Type||Artwork to accompany media release|
|Media of output||Online Artwork|
|Number of pages||1|
|Place of Publication||Melbourne Australia|
|Publication status||Published - 4 Jun 2021|