Accelerating the search for the missing proteins in the human proteome

Mark S. Baker; Seong Beom Ahn; Abidali Mohamedali; Mohammad T. Islam; David Cantor; Peter D. Verhaert; Susan Fanayan; Samridhi Sharma; Edouard C. Nice; Mark Connor; Shoba Ranganathan

doi:10.1038/ncomms14271

Accelerating the search for the missing proteins in the human proteome

Mark S. Baker, Seong Beom Ahn, Abidali Mohamedali, Mohammad T. Islam, David Cantor, Peter D. Verhaert, Susan Fanayan, Samridhi Sharma, Edouard C. Nice, Mark Connor, Shoba Ranganathan

Biochemistry & Molecular Biology

Research output: Contribution to journal › Review Article › Research › peer-review

57 Citations (Scopus)

Abstract

The Human Proteome Project (HPP) aims to discover high-stringency data for all proteins encoded by the human genome. Currently, B18% of the proteins in the human proteome (the missing proteins) do not have high-stringency evidence (for example, mass spectrometry) confirming their existence, while much additional information is available about many of these missing proteins. Here, we present MissingProteinPedia as a community resource to accelerate the discovery and understanding of these missing proteins.

Original language	English
Article number	14271
Number of pages	13
Journal	Nature Communications
Volume	8
DOIs	https://doi.org/10.1038/ncomms14271
Publication status	Published - 24 Jan 2017

Keywords

mass spectrometry
proteome
proteomics

Access to Document

10.1038/ncomms14271

97878898-oaFinal published version, 1.5 MB

Link to publication in Scopus

Cite this

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Accelerating the search for the missing proteins in the human proteome. / Baker, Mark S.; Ahn, Seong Beom; Mohamedali, Abidali; Islam, Mohammad T.; Cantor, David; Verhaert, Peter D.; Fanayan, Susan; Sharma, Samridhi; Nice, Edouard C.; Connor, Mark; Ranganathan, Shoba.

In: Nature Communications, Vol. 8, 14271, 24.01.2017.

Research output: Contribution to journal › Review Article › Research › peer-review

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AU - Fanayan, Susan

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