Many animal models have been developed to study the aetiology of fetal renal disease (Peters 2001; Chevalier 2004). Apart from the immediate effects on the functioning of the fetal and neonatal kidney, one also has to consider the potential permanent alterations brought about in the metanephros, and the likelihood that these changes will lead to accelerated renal damage with aging and increase the risk of cardiovascular disease (Woolf 2001; Eskild-Jensen et al. 2002; Chevalier 2004).
|Title of host publication||Factors Influencing Mammalian Kidney Development|
|Subtitle of host publication||Implications for Health in Adult Life|
|Number of pages||2|
|Publication status||Published - 3 Jun 2008|
|Name||Advances in Anatomy Embryology and Cell Biology|