Original language | English |
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Title of host publication | The ADME Encyclopedia |
Subtitle of host publication | A Comprehensive Guide on Biopharmacy and Pharmacokinetics |
Editors | Alan Talevi |
Place of Publication | Cham Switzerland |
Publisher | Springer |
Pages | 1-8 |
Number of pages | 8 |
ISBN (Print) | 978-3-030-51519-5 |
DOIs | |
Publication status | Published - 2021 |
Externally published | Yes |
Abstract
The quantity and functional capacity of adenosine triphosphate-binding cassette (ABC) efflux transporters at a cellular interface is not identical between two people or necessarily the same for one individual at two points in time. Transporter levels are known to change due to a variety of factors including age, sex, medical condition, and medication use. These variations may result in individual differences of drug pharmacokinetics between patients.