A transdiagnostic dimensional approach towards a neuropsychological assessment for addiction: an international Delphi consensus study

Murat Yücel, Erin Oldenhof, Serge H. Ahmed, David Belin, Joel Billieux, Henrietta Bowden-Jones, Adrian Carter, Samuel R. Chamberlain, Luke Clark, Jason Connor, Mark Daglish, Geert Dom, Pinhas Dannon, Theodora Duka, Maria Jose Fernandez-Serrano, Matt Field, Ingmar Franken, Rita Z. Goldstein, Raul Gonzalez, Anna E. Goudriaan & 21 others Jon E. Grant, Matthew J. Gullo, Robert Hester, David C. Hodgins, Bernard Le Foll, Rico S. C. Lee, Anne Lingford-Hughes, Valentina Lorenzetti, Scott J. Moeller, Marcus R. Munafò, Brian Odlaug, Marc N. Potenza, Rebecca Segrave, Zsuzsika Sjoerds, Nadia Solowij, Wim van den Brink, Ruth J. van Holst, Valerie Voon, Reinout Wiers, Leonardo F. Fontenelle, Antonio Verdejo-Garcia

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background: The US National Institutes of Mental Health Research Domain Criteria (RDoC) seek to stimulate research into biologically validated neuropsychological dimensions across mental illness symptoms and diagnoses. The RDoC framework comprises 39 functional constructs designed to be revised and refined, with the overall goal of improving diagnostic validity and treatments. This study aimed to reach a consensus among experts in the addiction field on the ‘primary’ RDoC constructs most relevant to substance and behavioural addictions. Methods: Forty-four addiction experts were recruited from Australia, Asia, Europe and the Americas. The Delphi technique was used to determine a consensus as to the degree of importance of each construct in understanding the essential dimensions underpinning addictive behaviours. Expert opinions were canvassed online over three rounds (97% completion rate), with each consecutive round offering feedback for experts to review their opinions. Results: Seven constructs were endorsed by ≥ 80% of experts as ‘primary’ to the understanding of addictive behaviour: five from the Positive Valence System (reward valuation, expectancy, action selection, reward learning, habit); one from the Cognitive Control System (response selection/inhibition); and one expert-initiated construct (compulsivity). These constructs were rated to be related differentially to stages of the addiction cycle, with some linked more closely to addiction onset and others more to chronicity. Experts agreed that these neuropsychological dimensions apply across a range of addictions. Conclusions: The study offers a novel and neuropsychologically informed theoretical framework, as well as a cogent step forward to test transdiagnostic concepts in addiction research, with direct implications for assessment, diagnosis, staging of disorder, and treatment.

Original languageEnglish
Number of pages15
JournalAddiction
DOIs
Publication statusAccepted/In press - 1 Jan 2018

Keywords

  • Addiction
  • assessment
  • cognition
  • compulsions
  • decision-making
  • habit
  • RDoC
  • reward
  • transdiagnostic

Cite this

Yücel, Murat ; Oldenhof, Erin ; Ahmed, Serge H. ; Belin, David ; Billieux, Joel ; Bowden-Jones, Henrietta ; Carter, Adrian ; Chamberlain, Samuel R. ; Clark, Luke ; Connor, Jason ; Daglish, Mark ; Dom, Geert ; Dannon, Pinhas ; Duka, Theodora ; Fernandez-Serrano, Maria Jose ; Field, Matt ; Franken, Ingmar ; Goldstein, Rita Z. ; Gonzalez, Raul ; Goudriaan, Anna E. ; Grant, Jon E. ; Gullo, Matthew J. ; Hester, Robert ; Hodgins, David C. ; Le Foll, Bernard ; Lee, Rico S. C. ; Lingford-Hughes, Anne ; Lorenzetti, Valentina ; Moeller, Scott J. ; Munafò, Marcus R. ; Odlaug, Brian ; Potenza, Marc N. ; Segrave, Rebecca ; Sjoerds, Zsuzsika ; Solowij, Nadia ; van den Brink, Wim ; van Holst, Ruth J. ; Voon, Valerie ; Wiers, Reinout ; Fontenelle, Leonardo F. ; Verdejo-Garcia, Antonio. / A transdiagnostic dimensional approach towards a neuropsychological assessment for addiction : an international Delphi consensus study. In: Addiction. 2018.
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abstract = "Background: The US National Institutes of Mental Health Research Domain Criteria (RDoC) seek to stimulate research into biologically validated neuropsychological dimensions across mental illness symptoms and diagnoses. The RDoC framework comprises 39 functional constructs designed to be revised and refined, with the overall goal of improving diagnostic validity and treatments. This study aimed to reach a consensus among experts in the addiction field on the ‘primary’ RDoC constructs most relevant to substance and behavioural addictions. Methods: Forty-four addiction experts were recruited from Australia, Asia, Europe and the Americas. The Delphi technique was used to determine a consensus as to the degree of importance of each construct in understanding the essential dimensions underpinning addictive behaviours. Expert opinions were canvassed online over three rounds (97{\%} completion rate), with each consecutive round offering feedback for experts to review their opinions. Results: Seven constructs were endorsed by ≥ 80{\%} of experts as ‘primary’ to the understanding of addictive behaviour: five from the Positive Valence System (reward valuation, expectancy, action selection, reward learning, habit); one from the Cognitive Control System (response selection/inhibition); and one expert-initiated construct (compulsivity). These constructs were rated to be related differentially to stages of the addiction cycle, with some linked more closely to addiction onset and others more to chronicity. Experts agreed that these neuropsychological dimensions apply across a range of addictions. Conclusions: The study offers a novel and neuropsychologically informed theoretical framework, as well as a cogent step forward to test transdiagnostic concepts in addiction research, with direct implications for assessment, diagnosis, staging of disorder, and treatment.",
keywords = "Addiction, assessment, cognition, compulsions, decision-making, habit, RDoC, reward, transdiagnostic",
author = "Murat Y{\"u}cel and Erin Oldenhof and Ahmed, {Serge H.} and David Belin and Joel Billieux and Henrietta Bowden-Jones and Adrian Carter and Chamberlain, {Samuel R.} and Luke Clark and Jason Connor and Mark Daglish and Geert Dom and Pinhas Dannon and Theodora Duka and Fernandez-Serrano, {Maria Jose} and Matt Field and Ingmar Franken and Goldstein, {Rita Z.} and Raul Gonzalez and Goudriaan, {Anna E.} and Grant, {Jon E.} and Gullo, {Matthew J.} and Robert Hester and Hodgins, {David C.} and {Le Foll}, Bernard and Lee, {Rico S. C.} and Anne Lingford-Hughes and Valentina Lorenzetti and Moeller, {Scott J.} and Munaf{\`o}, {Marcus R.} and Brian Odlaug and Potenza, {Marc N.} and Rebecca Segrave and Zsuzsika Sjoerds and Nadia Solowij and {van den Brink}, Wim and {van Holst}, {Ruth J.} and Valerie Voon and Reinout Wiers and Fontenelle, {Leonardo F.} and Antonio Verdejo-Garcia",
year = "2018",
month = "1",
day = "1",
doi = "10.1111/add.14424",
language = "English",
journal = "Addiction",
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publisher = "Wiley-Blackwell",

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Yücel, M, Oldenhof, E, Ahmed, SH, Belin, D, Billieux, J, Bowden-Jones, H, Carter, A, Chamberlain, SR, Clark, L, Connor, J, Daglish, M, Dom, G, Dannon, P, Duka, T, Fernandez-Serrano, MJ, Field, M, Franken, I, Goldstein, RZ, Gonzalez, R, Goudriaan, AE, Grant, JE, Gullo, MJ, Hester, R, Hodgins, DC, Le Foll, B, Lee, RSC, Lingford-Hughes, A, Lorenzetti, V, Moeller, SJ, Munafò, MR, Odlaug, B, Potenza, MN, Segrave, R, Sjoerds, Z, Solowij, N, van den Brink, W, van Holst, RJ, Voon, V, Wiers, R, Fontenelle, LF & Verdejo-Garcia, A 2018, 'A transdiagnostic dimensional approach towards a neuropsychological assessment for addiction: an international Delphi consensus study' Addiction. https://doi.org/10.1111/add.14424

A transdiagnostic dimensional approach towards a neuropsychological assessment for addiction : an international Delphi consensus study. / Yücel, Murat; Oldenhof, Erin; Ahmed, Serge H.; Belin, David; Billieux, Joel; Bowden-Jones, Henrietta; Carter, Adrian; Chamberlain, Samuel R.; Clark, Luke; Connor, Jason; Daglish, Mark; Dom, Geert; Dannon, Pinhas; Duka, Theodora; Fernandez-Serrano, Maria Jose; Field, Matt; Franken, Ingmar; Goldstein, Rita Z.; Gonzalez, Raul; Goudriaan, Anna E.; Grant, Jon E.; Gullo, Matthew J.; Hester, Robert; Hodgins, David C.; Le Foll, Bernard; Lee, Rico S. C.; Lingford-Hughes, Anne; Lorenzetti, Valentina; Moeller, Scott J.; Munafò, Marcus R.; Odlaug, Brian; Potenza, Marc N.; Segrave, Rebecca; Sjoerds, Zsuzsika; Solowij, Nadia; van den Brink, Wim; van Holst, Ruth J.; Voon, Valerie; Wiers, Reinout; Fontenelle, Leonardo F.; Verdejo-Garcia, Antonio.

In: Addiction, 01.01.2018.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - A transdiagnostic dimensional approach towards a neuropsychological assessment for addiction

T2 - an international Delphi consensus study

AU - Yücel, Murat

AU - Oldenhof, Erin

AU - Ahmed, Serge H.

AU - Belin, David

AU - Billieux, Joel

AU - Bowden-Jones, Henrietta

AU - Carter, Adrian

AU - Chamberlain, Samuel R.

AU - Clark, Luke

AU - Connor, Jason

AU - Daglish, Mark

AU - Dom, Geert

AU - Dannon, Pinhas

AU - Duka, Theodora

AU - Fernandez-Serrano, Maria Jose

AU - Field, Matt

AU - Franken, Ingmar

AU - Goldstein, Rita Z.

AU - Gonzalez, Raul

AU - Goudriaan, Anna E.

AU - Grant, Jon E.

AU - Gullo, Matthew J.

AU - Hester, Robert

AU - Hodgins, David C.

AU - Le Foll, Bernard

AU - Lee, Rico S. C.

AU - Lingford-Hughes, Anne

AU - Lorenzetti, Valentina

AU - Moeller, Scott J.

AU - Munafò, Marcus R.

AU - Odlaug, Brian

AU - Potenza, Marc N.

AU - Segrave, Rebecca

AU - Sjoerds, Zsuzsika

AU - Solowij, Nadia

AU - van den Brink, Wim

AU - van Holst, Ruth J.

AU - Voon, Valerie

AU - Wiers, Reinout

AU - Fontenelle, Leonardo F.

AU - Verdejo-Garcia, Antonio

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Background: The US National Institutes of Mental Health Research Domain Criteria (RDoC) seek to stimulate research into biologically validated neuropsychological dimensions across mental illness symptoms and diagnoses. The RDoC framework comprises 39 functional constructs designed to be revised and refined, with the overall goal of improving diagnostic validity and treatments. This study aimed to reach a consensus among experts in the addiction field on the ‘primary’ RDoC constructs most relevant to substance and behavioural addictions. Methods: Forty-four addiction experts were recruited from Australia, Asia, Europe and the Americas. The Delphi technique was used to determine a consensus as to the degree of importance of each construct in understanding the essential dimensions underpinning addictive behaviours. Expert opinions were canvassed online over three rounds (97% completion rate), with each consecutive round offering feedback for experts to review their opinions. Results: Seven constructs were endorsed by ≥ 80% of experts as ‘primary’ to the understanding of addictive behaviour: five from the Positive Valence System (reward valuation, expectancy, action selection, reward learning, habit); one from the Cognitive Control System (response selection/inhibition); and one expert-initiated construct (compulsivity). These constructs were rated to be related differentially to stages of the addiction cycle, with some linked more closely to addiction onset and others more to chronicity. Experts agreed that these neuropsychological dimensions apply across a range of addictions. Conclusions: The study offers a novel and neuropsychologically informed theoretical framework, as well as a cogent step forward to test transdiagnostic concepts in addiction research, with direct implications for assessment, diagnosis, staging of disorder, and treatment.

AB - Background: The US National Institutes of Mental Health Research Domain Criteria (RDoC) seek to stimulate research into biologically validated neuropsychological dimensions across mental illness symptoms and diagnoses. The RDoC framework comprises 39 functional constructs designed to be revised and refined, with the overall goal of improving diagnostic validity and treatments. This study aimed to reach a consensus among experts in the addiction field on the ‘primary’ RDoC constructs most relevant to substance and behavioural addictions. Methods: Forty-four addiction experts were recruited from Australia, Asia, Europe and the Americas. The Delphi technique was used to determine a consensus as to the degree of importance of each construct in understanding the essential dimensions underpinning addictive behaviours. Expert opinions were canvassed online over three rounds (97% completion rate), with each consecutive round offering feedback for experts to review their opinions. Results: Seven constructs were endorsed by ≥ 80% of experts as ‘primary’ to the understanding of addictive behaviour: five from the Positive Valence System (reward valuation, expectancy, action selection, reward learning, habit); one from the Cognitive Control System (response selection/inhibition); and one expert-initiated construct (compulsivity). These constructs were rated to be related differentially to stages of the addiction cycle, with some linked more closely to addiction onset and others more to chronicity. Experts agreed that these neuropsychological dimensions apply across a range of addictions. Conclusions: The study offers a novel and neuropsychologically informed theoretical framework, as well as a cogent step forward to test transdiagnostic concepts in addiction research, with direct implications for assessment, diagnosis, staging of disorder, and treatment.

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KW - assessment

KW - cognition

KW - compulsions

KW - decision-making

KW - habit

KW - RDoC

KW - reward

KW - transdiagnostic

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DO - 10.1111/add.14424

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JO - Addiction

JF - Addiction

SN - 0965-2140

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