A systematic review on human exposure to organophosphorus pesticides in Iran

Amir Shadboorestan, Hossein Molavi Vardanjani, Mohammad Hossain Abdollahi, Mohammad Hadi Goharbari, Narges Khanjani

Research output: Contribution to journalReview ArticleResearchpeer-review

12 Citations (Scopus)


Human exposure to organophosphorus (OP) pesticides is a serious health challenge. We conducted a systematic review by searching international and national databases for published literature on any human exposure to OPs in Iran from 1990 to March 2015. Qualified papers were in two categories including studies in which biomarkers of exposure were assessed (n = 13; total no. of subjects = 759) and studies that had reported prevalence of OPs-induced poisoning (OPP) and mortality (n = 26; total no. of subjects = 5428). The mean level of activity of acetyl-cholinesterase and butyryl-cholinesterase were 68.65% and 74.2%, respectively. Overall proportion (%) of OPP was estimated (16; 95% CI, 14 to 19).

Original languageEnglish
Pages (from-to)187-203
Number of pages17
JournalJournal of Environmental Science and Health, Part C: Environmental Carcinogenesis and Ecotoxicology Reviews
Issue number3
Publication statusPublished - 2 Jul 2016
Externally publishedYes


  • Iran
  • mortality
  • organophosphorus
  • poisoning prevalence
  • Systematic review

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