A system architecture for sharing de-identified, research-ready brain scans and health information across clinical imaging centers

Ann L. Chervenak, Theo G.M. Van Erp, Carl Kesselman, Mike D'Arcy, Janet Sobell, David Keator, Lisa Dahm, Jim Murry, Meng Law, Anton Hasso, Joseph Ames, Fabio MacCiardi, Steven G. Potkin

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

3 Citations (Scopus)


Progress in our understanding of brain disorders increasingly relies on the costly collection of large standardized brain magnetic resonance imaging (MRI) data sets. Moreover, the clinical interpretation of brain scans benefits from compare and contrast analyses of scans from patients with similar, and sometimes rare, demographic, diagnostic, and treatment status. A solution to both needs is to acquire standardized, research-ready clinical brain scans and to build the information technology infrastructure to share such scans, along with other pertinent information, across hospitals. This paper describes the design, deployment, and operation of a federated imaging system that captures and shares standardized, de-identified clinical brain images in a federation across multiple institutions. In addition to describing innovative aspects of the system architecture and our initial testing of the deployed infrastructure, we also describe the Standardized Imaging Protocol (SIP) developed for the project and our interactions with the Institutional Review Board (IRB) regarding handling patient data in the federated environment.

Original languageEnglish
Title of host publicationHealthGrid Applications and Technologies Meet Science Gateways for Life Sciences
PublisherIOS Press
Number of pages10
ISBN (Print)9781614990536
Publication statusPublished - 1 Jan 2012
Externally publishedYes
Event10th HealthGrid Conference and the 4th International Workshop on Science Gateways for Life Sciences, IWSG-Life 2012 - Amsterdam, Netherlands
Duration: 21 May 201225 May 2012

Publication series

NameStudies in Health Technology and Informatics
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365


Conference10th HealthGrid Conference and the 4th International Workshop on Science Gateways for Life Sciences, IWSG-Life 2012


  • Architecture
  • Brain
  • De-identification
  • Federation
  • Health
  • Hospitals
  • Imaging
  • Infrastructure
  • MRI
  • Open source
  • Pilot
  • Protocol
  • Sharing
  • Standardization

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