@article{be4aeae03e2149ac943748ee90ec45a7,
title = "A substantial number of patients with rest pain, ulceration or gangrene are unable to undergo current non-invasive perfusion testing—Could another modality be utilised?",
abstract = "Rest pain, ulceration and gangrene are hallmark features of chronic limb-threatening ischaemia (CLTI). Wound healing can be challenging, and this is compounded by an inability to measure lower limb perfusion via non-invasive tools such as toe pressure (TP). Novel perfusion tests, such as pedal acceleration time (PAT), may overcome some limitations. This study aimed to quantify the proportion of patients with CLTI that were unable to undergo TP measurement. Over a three-year duration, 344 consecutive patients with CLTI underwent PAT assessment (403 limbs). Overall, 32\% of limbs were unable to undergo first toe TP, and 12.9\% were unable to undergo first and second toe TP due to forefoot/digit amputation or tissue loss. Inability to measure first toe TP disproportionately impacted CLTI patients with diabetes compared to patients without diabetes (39.6\% limbs (106/268); vs. 17\% limbs (23/135); p < 0.001). Novel modalities may provide a useful tool for assessing perfusion in CLTI.",
keywords = "chronic limb-threatening ischaemia, diabetic wound care, peripheral artery disease, wound, wound management",
author = "Odette Hart and Qiantai Hong and Lee, \{Khai Tuck\} and Sinead Gormley and Peta Tehan and Jill Sommerset and Manar Khashram",
note = "Funding Information: OH is the recipient of the Reg Worcester Research Scholarship 2023 and the Professor Philip Walker Vascular Surgery Research Scholarship 2022 and 2021, with support from the Royal Australasian College of Surgeons and the Foundation for Surgery. Open access publishing facilitated by The University of Auckland, as part of the Wiley - The University of Auckland agreement via the Council of Australian University Librarians. Funding Information: OH is the recipient of the Reg Worcester Research Scholarship 2023 and the Professor Philip Walker Vascular Surgery Research Scholarship 2022 and 2021, with support from the Royal Australasian College of Surgeons and the Foundation for Surgery. Open access publishing facilitated by The University of Auckland, as part of the Wiley ‐ The University of Auckland agreement via the Council of Australian University Librarians. Publisher Copyright: {\textcopyright} 2023 The Authors. Wound Repair and Regeneration published by Wiley Periodicals LLC on behalf of The Wound Healing Society.",
year = "2023",
month = nov,
day = "1",
doi = "10.1111/wrr.13138",
language = "English",
volume = "31",
pages = "779--782",
journal = "Wound Repair and Regeneration",
issn = "1067-1927",
publisher = "Wiley-Blackwell",
number = "6",
}