A study on the correlates of habit-, reward-, and fear-related motivations in alcohol use disorder

Marcelo Piquet-Pessôa, Samuel R. Chamberlain, Rico S. C. Lee, Gabriela M. Ferreira, Marcelo S. Cruz, Ana P. Ribeiro, Gabriela B. De Menezes, Lucy Albertella, Murat Yücel, Leonardo F. Fontenelle

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Objective.We assessed self-reported drives for alcohol use and their impact on clinical features of alcohol use disorder (AUD) patients. Our prediction was that, in contrast to "affectively" (reward or fear) driven drinking, "habitual" drinking would be associated with worse clinical features in relation to alcohol use and higher occurrence of associated psychiatric symptoms.Methods.Fifty-eight Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) alcohol abuse patients were assessed with a comprehensive battery of reward- and fear-based behavioral tendencies. An 18-item self-report instrument (the Habit, Reward and Fear Scale; HRFS) was employed to quantify affective (fear or reward) and non-affective (habitual) motivations for alcohol use. To characterize clinical and demographic measures associated with habit, reward, and fear, we conducted a partial least squares analysis.Results.Habitual alcohol use was significantly associated with the severity of alcohol dependence reflected across a range of domains and with lower number of detoxifications across multiple settings. In contrast, reward-driven alcohol use was associated with a single domain of alcohol dependence, reward-related behavioral tendencies, and lower number of detoxifications.Conclusion.These results seem to be consistent with a shift from goal-directed to habit-driven alcohol use with severity and progression of addiction, complementing preclinical work and informing biological models of addiction. Both reward-related and habit-driven alcohol use were associated with lower number of detoxifications, perhaps stemming from more benign course for the reward-related and lack of treatment engagement for the habit-related alcohol abuse group. Future work should further explore the role of habit in this and other addictive disorders, and in obsessive-compulsive related disorders.

Original languageEnglish
Number of pages8
JournalCNS Spectrums
DOIs
Publication statusAccepted/In press - 27 Mar 2019

Keywords

  • Classification
  • dependence
  • diagnosis
  • substance abuse
  • typology

Cite this

Piquet-Pessôa, Marcelo ; Chamberlain, Samuel R. ; Lee, Rico S. C. ; Ferreira, Gabriela M. ; Cruz, Marcelo S. ; Ribeiro, Ana P. ; De Menezes, Gabriela B. ; Albertella, Lucy ; Yücel, Murat ; Fontenelle, Leonardo F. / A study on the correlates of habit-, reward-, and fear-related motivations in alcohol use disorder. In: CNS Spectrums. 2019.
@article{305b5d96a38e49c5ad35befa9a8c66f7,
title = "A study on the correlates of habit-, reward-, and fear-related motivations in alcohol use disorder",
abstract = "Objective.We assessed self-reported drives for alcohol use and their impact on clinical features of alcohol use disorder (AUD) patients. Our prediction was that, in contrast to {"}affectively{"} (reward or fear) driven drinking, {"}habitual{"} drinking would be associated with worse clinical features in relation to alcohol use and higher occurrence of associated psychiatric symptoms.Methods.Fifty-eight Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) alcohol abuse patients were assessed with a comprehensive battery of reward- and fear-based behavioral tendencies. An 18-item self-report instrument (the Habit, Reward and Fear Scale; HRFS) was employed to quantify affective (fear or reward) and non-affective (habitual) motivations for alcohol use. To characterize clinical and demographic measures associated with habit, reward, and fear, we conducted a partial least squares analysis.Results.Habitual alcohol use was significantly associated with the severity of alcohol dependence reflected across a range of domains and with lower number of detoxifications across multiple settings. In contrast, reward-driven alcohol use was associated with a single domain of alcohol dependence, reward-related behavioral tendencies, and lower number of detoxifications.Conclusion.These results seem to be consistent with a shift from goal-directed to habit-driven alcohol use with severity and progression of addiction, complementing preclinical work and informing biological models of addiction. Both reward-related and habit-driven alcohol use were associated with lower number of detoxifications, perhaps stemming from more benign course for the reward-related and lack of treatment engagement for the habit-related alcohol abuse group. Future work should further explore the role of habit in this and other addictive disorders, and in obsessive-compulsive related disorders.",
keywords = "Classification, dependence, diagnosis, substance abuse, typology",
author = "Marcelo Piquet-Pess{\^o}a and Chamberlain, {Samuel R.} and Lee, {Rico S. C.} and Ferreira, {Gabriela M.} and Cruz, {Marcelo S.} and Ribeiro, {Ana P.} and {De Menezes}, {Gabriela B.} and Lucy Albertella and Murat Y{\"u}cel and Fontenelle, {Leonardo F.}",
year = "2019",
month = "3",
day = "27",
doi = "10.1017/S1092852918001554",
language = "English",
journal = "CNS Spectrums",
issn = "1092-8529",
publisher = "Cambridge University Press",

}

A study on the correlates of habit-, reward-, and fear-related motivations in alcohol use disorder. / Piquet-Pessôa, Marcelo; Chamberlain, Samuel R.; Lee, Rico S. C.; Ferreira, Gabriela M.; Cruz, Marcelo S.; Ribeiro, Ana P.; De Menezes, Gabriela B.; Albertella, Lucy; Yücel, Murat; Fontenelle, Leonardo F.

In: CNS Spectrums, 27.03.2019.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - A study on the correlates of habit-, reward-, and fear-related motivations in alcohol use disorder

AU - Piquet-Pessôa, Marcelo

AU - Chamberlain, Samuel R.

AU - Lee, Rico S. C.

AU - Ferreira, Gabriela M.

AU - Cruz, Marcelo S.

AU - Ribeiro, Ana P.

AU - De Menezes, Gabriela B.

AU - Albertella, Lucy

AU - Yücel, Murat

AU - Fontenelle, Leonardo F.

PY - 2019/3/27

Y1 - 2019/3/27

N2 - Objective.We assessed self-reported drives for alcohol use and their impact on clinical features of alcohol use disorder (AUD) patients. Our prediction was that, in contrast to "affectively" (reward or fear) driven drinking, "habitual" drinking would be associated with worse clinical features in relation to alcohol use and higher occurrence of associated psychiatric symptoms.Methods.Fifty-eight Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) alcohol abuse patients were assessed with a comprehensive battery of reward- and fear-based behavioral tendencies. An 18-item self-report instrument (the Habit, Reward and Fear Scale; HRFS) was employed to quantify affective (fear or reward) and non-affective (habitual) motivations for alcohol use. To characterize clinical and demographic measures associated with habit, reward, and fear, we conducted a partial least squares analysis.Results.Habitual alcohol use was significantly associated with the severity of alcohol dependence reflected across a range of domains and with lower number of detoxifications across multiple settings. In contrast, reward-driven alcohol use was associated with a single domain of alcohol dependence, reward-related behavioral tendencies, and lower number of detoxifications.Conclusion.These results seem to be consistent with a shift from goal-directed to habit-driven alcohol use with severity and progression of addiction, complementing preclinical work and informing biological models of addiction. Both reward-related and habit-driven alcohol use were associated with lower number of detoxifications, perhaps stemming from more benign course for the reward-related and lack of treatment engagement for the habit-related alcohol abuse group. Future work should further explore the role of habit in this and other addictive disorders, and in obsessive-compulsive related disorders.

AB - Objective.We assessed self-reported drives for alcohol use and their impact on clinical features of alcohol use disorder (AUD) patients. Our prediction was that, in contrast to "affectively" (reward or fear) driven drinking, "habitual" drinking would be associated with worse clinical features in relation to alcohol use and higher occurrence of associated psychiatric symptoms.Methods.Fifty-eight Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) alcohol abuse patients were assessed with a comprehensive battery of reward- and fear-based behavioral tendencies. An 18-item self-report instrument (the Habit, Reward and Fear Scale; HRFS) was employed to quantify affective (fear or reward) and non-affective (habitual) motivations for alcohol use. To characterize clinical and demographic measures associated with habit, reward, and fear, we conducted a partial least squares analysis.Results.Habitual alcohol use was significantly associated with the severity of alcohol dependence reflected across a range of domains and with lower number of detoxifications across multiple settings. In contrast, reward-driven alcohol use was associated with a single domain of alcohol dependence, reward-related behavioral tendencies, and lower number of detoxifications.Conclusion.These results seem to be consistent with a shift from goal-directed to habit-driven alcohol use with severity and progression of addiction, complementing preclinical work and informing biological models of addiction. Both reward-related and habit-driven alcohol use were associated with lower number of detoxifications, perhaps stemming from more benign course for the reward-related and lack of treatment engagement for the habit-related alcohol abuse group. Future work should further explore the role of habit in this and other addictive disorders, and in obsessive-compulsive related disorders.

KW - Classification

KW - dependence

KW - diagnosis

KW - substance abuse

KW - typology

UR - http://www.scopus.com/inward/record.url?scp=85063683691&partnerID=8YFLogxK

U2 - 10.1017/S1092852918001554

DO - 10.1017/S1092852918001554

M3 - Article

JO - CNS Spectrums

JF - CNS Spectrums

SN - 1092-8529

ER -