A simplified state-space model of biventricular assist device-cardiovascular system interaction

Vivian C.A. Koh, Einly Lim, Boon Chiang Ng, Yong Kuen Ho, Nigel H. Lovell

    Research output: Chapter in Book/Report/Conference proceedingConference PaperOther

    4 Citations (Scopus)

    Abstract

    A simplified state-space model of biventricular assist device (BiVAD)-cardiovascular system (CVS) interaction is presented. The state-space equations includes a six-compartments CVS model incorporating the ventricles, the pulmonary and systemic circulations as well as the non-linear behavior of the valve flow, together with a left ventricular assist device (LVAD) and a right ventricular assist device (RVAD) component. The left and right pump speeds serve as the input variables for the state-space model. The model is simulated with three operational modes, i.e. (i) RVAD speed < LVAD speed, (ii) same LVAD and RVAD speeds and (iii) inclusion of a 6 mm restriction at the right outflow cannula. The effect of RVAD speed variation on the steady state hemodynamics is also studied with and without an outflow banding restriction. Our simulated results are validated with experimental data obtained from clinical, in vivo and in vitro studies provided in the literatures. We observed that despite its simplicity, the model is able to reproduce the observed trends in the reported studies, thus making it feasible for the development of robust yet practical control algorithms.

    Original languageEnglish
    Title of host publication2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
    PublisherIEEE, Institute of Electrical and Electronics Engineers
    Pages4317-4320
    Number of pages4
    ISBN (Electronic)9781457702204
    DOIs
    Publication statusPublished - 2016
    EventInternational Conference of the IEEE Engineering in Medicine and Biology Society 2016 - Walt Disney World Resort, Orlando, United States of America
    Duration: 16 Aug 201620 Aug 2016
    Conference number: 38th
    https://embc.embs.org/2016/
    https://ieeexplore.ieee.org/xpl/conhome/7580725/proceeding (Proceedings)

    Publication series

    NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
    Volume2016-October
    ISSN (Print)1557-170X

    Conference

    ConferenceInternational Conference of the IEEE Engineering in Medicine and Biology Society 2016
    Abbreviated titleEMBC 2016
    CountryUnited States of America
    CityOrlando
    Period16/08/1620/08/16
    Internet address

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