A simple amine protection strategy for olefin metathesis reactions

Clint Peter Woodward, Nicolas D Spiccia, William Roy Jackson, Andrea Jane Robinson

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Abstract

Acyclic diamines are valuable feedstocks for polyamide synthesis. Ruthenium-alkylidene catalysed cross metathesis of amino alkenes is problematic and acyl derivatisation can result in less efficient syntheses, poor catalyst turnover and isomerisation. Temporary amine masking via stable and soluble ammonium salts delivers cyclic and acyclic aminoalkenes in high yield and purity.
Original languageEnglish
Pages (from-to)779 - 781
Number of pages3
JournalChemical Communications
Volume47
Issue number2
DOIs
Publication statusPublished - 2011

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