TY - JOUR
T1 - A review on the management of migraine in the Avicenna’s Canon of Medicine
AU - Zargaran, Arman
AU - Borhani-Haghighi, Afshin
AU - Faridi, Pouya
AU - Daneshamouz, Saeid
AU - Mohagheghzadeh, Abdolali
PY - 2016/3/1
Y1 - 2016/3/1
N2 - Migraine is a common type of headache which has a deep history dating back thousands of years. Avicenna (980–1032), a Persian scholar, made a great contribution to neurology including headache and migraine. The aim of this study is to consider Avicenna’s description about migraine (Shaghighe in Persian language) including definition, etiology and intervention. Also, his definition and treatment approaches were considered based on current concepts and findings. Although Avicenna believed in humoral theory and divided migraine into two categories, hot and cold, and suggested special treatments for them as well as general considerations, most of his definitions and explained pathologies are supported by current concepts of medicine. He believed that the migraine can result from bone of skull and also intra-parenchymal; or from skull underneath membrane (dura-mater); or reaching substances from the painful side or from outer vein and arteries (extra cranial); or from brain and meninges (pia-mater). Furthermore, current findings show most medicinal plants mentioned by Avicenna for the treatment of migraine can have potentially significant effects such as remedies which stop central and peripheral sensitization [anti-neuroinflammatory agents, decreasing nitric oxide level, cyclooxygenase (COX)-2 inhibitors], as well as serotonergics, neuroprotective agents and analgesics.
AB - Migraine is a common type of headache which has a deep history dating back thousands of years. Avicenna (980–1032), a Persian scholar, made a great contribution to neurology including headache and migraine. The aim of this study is to consider Avicenna’s description about migraine (Shaghighe in Persian language) including definition, etiology and intervention. Also, his definition and treatment approaches were considered based on current concepts and findings. Although Avicenna believed in humoral theory and divided migraine into two categories, hot and cold, and suggested special treatments for them as well as general considerations, most of his definitions and explained pathologies are supported by current concepts of medicine. He believed that the migraine can result from bone of skull and also intra-parenchymal; or from skull underneath membrane (dura-mater); or reaching substances from the painful side or from outer vein and arteries (extra cranial); or from brain and meninges (pia-mater). Furthermore, current findings show most medicinal plants mentioned by Avicenna for the treatment of migraine can have potentially significant effects such as remedies which stop central and peripheral sensitization [anti-neuroinflammatory agents, decreasing nitric oxide level, cyclooxygenase (COX)-2 inhibitors], as well as serotonergics, neuroprotective agents and analgesics.
KW - Avicenna
KW - History of medicine
KW - Medieval period
KW - Migraine
KW - Persian medicine
UR - http://www.scopus.com/inward/record.url?scp=84961051449&partnerID=8YFLogxK
U2 - 10.1007/s10072-016-2498-9
DO - 10.1007/s10072-016-2498-9
M3 - Review Article
C2 - 26861565
AN - SCOPUS:84961051449
VL - 37
SP - 471
EP - 478
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 3
ER -