A randomised controlled trial of an open lung strategy with staircase recruitment, titrated PEEP and targeted low airway pressures in patients with acute respiratory distress syndrome

Research output: Contribution to journalArticleResearchpeer-review

93 Citations (Scopus)


Introduction Tidal volume and plateau pressure minimisation are the standard components of a protective lung ventilation strategy for patients with acute respiratory distress syndrome (ARDS). Open lung strategies, including higher positive end-expiratory pressure (PEEP) and recruitment maneuvers to date have not proven efficacious. This study examines the effectiveness and safety of a novel open lung strategy, which includes permissive hypercapnia, staircase recruitment maneuvers (SRM) and low airway pressure with PEEP titration.
Original languageEnglish
Article numberR133
Number of pages9
JournalCritical Care
Issue number3
Publication statusPublished - 2011

Cite this