A Protein Disulfide Isomerase Controls Neuronal Migration through Regulation of Wnt Secretion

Nanna Torpe; Sandeep Gopal; Oguzhan Baltaci; Lorenzo Rella; Ava Handley; Hendrik C. Korswagen; Roger Pocock

doi:10.1016/j.celrep.2019.02.072

A Protein Disulfide Isomerase Controls Neuronal Migration through Regulation of Wnt Secretion

Nanna Torpe, Sandeep Gopal, Oguzhan Baltaci, Lorenzo Rella, Ava Handley, Hendrik C. Korswagen, Roger Pocock

Research output: Contribution to journal › Article › Research › peer-review

10 Citations (Scopus)

Abstract

Wnt proteins are conserved regulators of developmental patterning. Here, Torpe et al. report that Wnt secretion is regulated by a protein disulfide isomerase in Caenorhabditis elegans and human cells.

Original language	English
Pages (from-to)	3183-3190
Number of pages	8
Journal	Cell Reports
Volume	26
Issue number	12
DOIs	https://doi.org/10.1016/j.celrep.2019.02.072
Publication status	Published - 19 Mar 2019

Keywords

neuronal migration
protein disulfide isomerase
Wnt morphogen
Wnt secretion

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10.1016/j.celrep.2019.02.072

263624125-oaFinal published version, 2.21 MB

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title = "A Protein Disulfide Isomerase Controls Neuronal Migration through Regulation of Wnt Secretion",

abstract = "Wnt proteins are conserved regulators of developmental patterning. Here, Torpe et al. report that Wnt secretion is regulated by a protein disulfide isomerase in Caenorhabditis elegans and human cells.",

keywords = "neuronal migration, protein disulfide isomerase, Wnt morphogen, Wnt secretion",

author = "Nanna Torpe and Sandeep Gopal and Oguzhan Baltaci and Lorenzo Rella and Ava Handley and Korswagen, {Hendrik C.} and Roger Pocock",

year = "2019",

month = mar,

day = "19",

doi = "10.1016/j.celrep.2019.02.072",

language = "English",

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T1 - A Protein Disulfide Isomerase Controls Neuronal Migration through Regulation of Wnt Secretion

AU - Torpe, Nanna

AU - Gopal, Sandeep

AU - Baltaci, Oguzhan

AU - Rella, Lorenzo

AU - Handley, Ava

AU - Korswagen, Hendrik C.

AU - Pocock, Roger

PY - 2019/3/19

Y1 - 2019/3/19

N2 - Wnt proteins are conserved regulators of developmental patterning. Here, Torpe et al. report that Wnt secretion is regulated by a protein disulfide isomerase in Caenorhabditis elegans and human cells.

AB - Wnt proteins are conserved regulators of developmental patterning. Here, Torpe et al. report that Wnt secretion is regulated by a protein disulfide isomerase in Caenorhabditis elegans and human cells.

KW - neuronal migration

KW - protein disulfide isomerase

KW - Wnt morphogen

KW - Wnt secretion

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U2 - 10.1016/j.celrep.2019.02.072

DO - 10.1016/j.celrep.2019.02.072

M3 - Article

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VL - 26

SP - 3183

EP - 3190

JO - Cell Reports

JF - Cell Reports

SN - 2211-1247

IS - 12

ER -

A Protein Disulfide Isomerase Controls Neuronal Migration through Regulation of Wnt Secretion

Abstract

Keywords

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CALCIUM-MEDIATED REGULATION OF STEM CELL DEVELOPMENT

Role of Transient Ca2+ in Transcriptional Wiring of Stem Cells

Decoding mechanisms of brain-intestinal communication

Cite this

A Protein Disulfide Isomerase Controls Neuronal Migration through Regulation of Wnt Secretion

Abstract

Keywords

Access to Document

Other files and links

Projects

CALCIUM-MEDIATED REGULATION OF STEM CELL DEVELOPMENT

Role of Transient Ca2+ in Transcriptional Wiring of Stem Cells

Decoding mechanisms of brain-intestinal communication

Cite this