A Protein Disulfide Isomerase Controls Neuronal Migration through Regulation of Wnt Secretion

Nanna Torpe, Sandeep Gopal, Oguzhan Baltaci, Lorenzo Rella, Ava Handley, Hendrik C. Korswagen, Roger Pocock

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Wnt proteins are conserved regulators of developmental patterning. Here, Torpe et al. report that Wnt secretion is regulated by a protein disulfide isomerase in Caenorhabditis elegans and human cells.

Original languageEnglish
Pages (from-to)3183-3190
Number of pages8
JournalCell Reports
Volume26
Issue number12
DOIs
Publication statusPublished - 19 Mar 2019

Keywords

  • neuronal migration
  • protein disulfide isomerase
  • Wnt morphogen
  • Wnt secretion

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