A polynomial model of patient-specific breathing effort during controlled mechanical ventilation

Daniel P. Redmond, Paul D. Docherty, Yeong Shiong Chiew, J. Geoffrey Chase

Research output: Chapter in Book/Report/Conference proceedingConference PaperOther

5 Citations (Scopus)

Abstract

Patient breathing efforts occurring during controlled ventilation causes perturbations in pressure data, which cause erroneous parameter estimation in conventional models of respiratory mechanics. A polynomial model of patient effort can be used to capture breath-specific effort and underlying lung condition. An iterative multiple linear regression is used to identify the model in clinical volume controlled data. The polynomial model has lower fitting error and more stable estimates of respiratory elastance and resistance in the presence of patient effort than the conventional single compartment model. However, the polynomial model can converge to poor parameter estimation when patient efforts occur very early in the breath, or for long duration. The model of patient effort can provide clinical benefits by providing accurate respiratory mechanics estimation and monitoring of breath-to-breath patient effort, which can be used by clinicians to guide treatment.

Original languageEnglish
Title of host publication2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
PublisherIEEE, Institute of Electrical and Electronics Engineers
Pages4532-4535
Number of pages4
ISBN (Electronic)9781424492718
DOIs
Publication statusPublished - 4 Nov 2015
Externally publishedYes
EventInternational Conference of the IEEE Engineering in Medicine and Biology Society 2015 - Milan, Italy
Duration: 25 Aug 201529 Aug 2015
Conference number: 37th
https://embc.embs.org/2015/
https://ieeexplore.ieee.org/xpl/conhome/7302811/proceeding (Proceedings)

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume2015-November
ISSN (Print)1557-170X

Conference

ConferenceInternational Conference of the IEEE Engineering in Medicine and Biology Society 2015
Abbreviated titleEMBC 2015
CountryItaly
CityMilan
Period25/08/1529/08/15
Other37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS). Our Annual Conference (known as EMBC) is a premier international conference in biomedical engineering, and has been strategically held in different locations around the world, including Chicago, Osaka, San Diego, Boston, Buenos Aires, Minneapolis, Vancouver, Lyon, New York, and Shanghai over the last 10 years.
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