A pharmacological approach to first aid treatment for snakebite

Megan E. Saul, Paul A. Thomas, Peter J. Dosen, Geoffrey K. Isbister, Margaret A O'Leary, Ian M Whyte, Sally A. McFadden, Dirk F. Van Helden

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Abstract

Snake venom toxins first transit the lymphatic system before entering the bloodstream. Ointment containing a nitric oxide donor, which impedes the intrinsic lymphatic pump, prolonged lymph transit time in rats and humans and also increased rat survival time after injection of venom. This pharmacological approach should give snakebite victims more time to obtain medical care and antivenom treatment.

Original languageEnglish
Pages (from-to)809-811
Number of pages3
JournalNature Medicine
Volume17
Issue number7
DOIs
Publication statusPublished - Jul 2011
Externally publishedYes

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