Abstract
In order to increase the loading efficiency of drug carriers, here we demonstrated a microfluidic method to fabricate an asymmetric vesicle, which contains trichloro(1H,1H,2H,2H-perfluoroocty-l)silane (TPS) inner leaflet and lipid outer leaflet. The asymmetric vesicle was characterised by fluorescence microscopy and Fourier transform infra-red spectrum. In vitro cytotoxicity of the vesicles carrying 5-fluorouacil (5-FU) has also been studied.
Original language | English |
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Pages (from-to) | 663-668 |
Number of pages | 6 |
Journal | Journal of Microencapsulation |
Volume | 33 |
Issue number | 7 |
DOIs | |
Publication status | Published - 2 Oct 2016 |
Keywords
- asymmetric vesicles
- drug delivery
- Lipid
- microfluidics
- self-assembly