TY - JOUR
T1 - A pathogenic hierarchy for synovial fibroblasts in rheumatoid arthritis
AU - Abuwarwar, Mohammed H.
AU - Knoblich, Konstantin
AU - Fletcher, Anne L.
PY - 2018/11
Y1 - 2018/11
N2 - Rheumatoid arthritis (RA) is a chronic autoimmune disorder that affects 0.5–1% of the world's population (1). It is characterized by inflammation and progressive destruction of joints (1). Synovial fibroblasts play important roles in initiating and driving RA by secreting inflammatory cytokines and chemokines, degrading cartilage, and stimulating osteoclasts that lead to bone erosion (2).
AB - Rheumatoid arthritis (RA) is a chronic autoimmune disorder that affects 0.5–1% of the world's population (1). It is characterized by inflammation and progressive destruction of joints (1). Synovial fibroblasts play important roles in initiating and driving RA by secreting inflammatory cytokines and chemokines, degrading cartilage, and stimulating osteoclasts that lead to bone erosion (2).
U2 - 10.21037/atm.2018.10.49
DO - 10.21037/atm.2018.10.49
M3 - Editorial
SN - 2305-5847
VL - 6
JO - Annals of Translational Medicine
JF - Annals of Translational Medicine
IS - Sup 1
ER -