A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane

Martti Vaara; Osmo Siikanen; Juha Apajalahti; John Fox; Niels Frimodt-Moller; Fiona Hui He; Anima Poudyal; Jian Li; Roger Leigh Nation; Timo Vaara

doi:10.1128/AAC.01439-09

A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane

Martti Vaara, Osmo Siikanen, Juha Apajalahti, John Fox, Niels Frimodt-Moller, Fiona Hui He, Anima Poudyal, Jian Li, Roger Leigh Nation, Timo Vaara

Centre for Medicine Use and Safety

Research output: Contribution to journal › Article › Research › peer-review

99 Citations (Scopus)

Original language	English
Pages (from-to)	3341 - 3346
Number of pages	6
Journal	Antimicrobial Agents and Chemotherapy
Volume	54
Issue number	8
DOIs	https://doi.org/10.1128/AAC.01439-09
Publication status	Published - 2010

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10.1128/AAC.01439-09

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Vaara, M., Siikanen, O., Apajalahti, J., Fox, J., Frimodt-Moller, N., He, F. H., Poudyal, A., Li, J., Nation, R. L., & Vaara, T. (2010). A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane. Antimicrobial Agents and Chemotherapy, 54(8), 3341 - 3346. https://doi.org/10.1128/AAC.01439-09

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title = "A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane",

author = "Martti Vaara and Osmo Siikanen and Juha Apajalahti and John Fox and Niels Frimodt-Moller and He, {Fiona Hui} and Anima Poudyal and Jian Li and Nation, {Roger Leigh} and Timo Vaara",

year = "2010",

doi = "10.1128/AAC.01439-09",

language = "English",

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Vaara, M, Siikanen, O, Apajalahti, J, Fox, J, Frimodt-Moller, N, He, FH, Poudyal, A, Li, J , Nation, RL & Vaara, T 2010, 'A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane', Antimicrobial Agents and Chemotherapy, vol. 54, no. 8, pp. 3341 - 3346. https://doi.org/10.1128/AAC.01439-09

A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane. / Vaara, Martti; Siikanen, Osmo; Apajalahti, Juha et al.
In: Antimicrobial Agents and Chemotherapy, Vol. 54, No. 8, 2010, p. 3341 - 3346.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane

AU - Vaara, Martti

AU - Siikanen, Osmo

AU - Apajalahti, Juha

AU - Fox, John

AU - Frimodt-Moller, Niels

AU - He, Fiona Hui

AU - Poudyal, Anima

AU - Li, Jian

AU - Nation, Roger Leigh

AU - Vaara, Timo

PY - 2010

Y1 - 2010

U2 - 10.1128/AAC.01439-09

DO - 10.1128/AAC.01439-09

M3 - Article

SN - 0066-4804

VL - 54

SP - 3341

EP - 3346

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 8

ER -