A novel multicomponent microwave-assisted synthesis of 5-aza-adenines

Anton V Dolzhenko; Svetlana A Kalinina; Dmitrii V Kalinin

doi:10.1039/c3ra41932k

A novel multicomponent microwave-assisted synthesis of 5-aza-adenines

Anton V Dolzhenko
, Svetlana A Kalinina
, Dmitrii V Kalinin

Research output: Contribution to journal › Article › Research › peer-review

33 Citations (Scopus)

Abstract

A novel multicomponent strategy for the efficient synthesis of 5-aza-adenines was developed. 5-Aza-adenines were prepared in a one-pot fashion from 5-amino-1,2,4-triazoles, cyanamide and triethyl orthoformate under microwave irradiation. The operational simplicity, efficiency and accessibility of this method make it highly attractive for the generation of bioactive compound libraries.

Original language	English
Pages (from-to)	15850 - 15855
Number of pages	6
Journal	RSC Advances
Volume	3
Issue number	36
DOIs	https://doi.org/10.1039/c3ra41932k
Publication status	Published - 2013

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title = "A novel multicomponent microwave-assisted synthesis of 5-aza-adenines",

abstract = "A novel multicomponent strategy for the efficient synthesis of 5-aza-adenines was developed. 5-Aza-adenines were prepared in a one-pot fashion from 5-amino-1,2,4-triazoles, cyanamide and triethyl orthoformate under microwave irradiation. The operational simplicity, efficiency and accessibility of this method make it highly attractive for the generation of bioactive compound libraries.",

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AU - Kalinina, Svetlana A

AU - Kalinin, Dmitrii V

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Y1 - 2013

N2 - A novel multicomponent strategy for the efficient synthesis of 5-aza-adenines was developed. 5-Aza-adenines were prepared in a one-pot fashion from 5-amino-1,2,4-triazoles, cyanamide and triethyl orthoformate under microwave irradiation. The operational simplicity, efficiency and accessibility of this method make it highly attractive for the generation of bioactive compound libraries.

AB - A novel multicomponent strategy for the efficient synthesis of 5-aza-adenines was developed. 5-Aza-adenines were prepared in a one-pot fashion from 5-amino-1,2,4-triazoles, cyanamide and triethyl orthoformate under microwave irradiation. The operational simplicity, efficiency and accessibility of this method make it highly attractive for the generation of bioactive compound libraries.

UR - http://pubs.rsc.org/en/content/articlepdf/2013/RA/C3RA41932K

U2 - 10.1039/c3ra41932k

DO - 10.1039/c3ra41932k

M3 - Article

SN - 2046-2069

VL - 3

SP - 15850

EP - 15855

JO - RSC Advances

JF - RSC Advances

IS - 36

ER -

A novel multicomponent microwave-assisted synthesis of 5-aza-adenines

Abstract

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