A novel multicomponent microwave-assisted synthesis of 5-aza-adenines

Anton V Dolzhenko, Svetlana A Kalinina, Dmitrii V Kalinin

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    22 Citations (Scopus)


    A novel multicomponent strategy for the efficient synthesis of 5-aza-adenines was developed. 5-Aza-adenines were prepared in a one-pot fashion from 5-amino-1,2,4-triazoles, cyanamide and triethyl orthoformate under microwave irradiation. The operational simplicity, efficiency and accessibility of this method make it highly attractive for the generation of bioactive compound libraries.
    Original languageEnglish
    Pages (from-to)15850 - 15855
    Number of pages6
    JournalRSC Advances
    Issue number36
    Publication statusPublished - 2013

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