A Novel Integrated Cognitive-Behavioral Therapy for Anxiety and Medication Adherence Among Persons Living With HIV/AIDS

Charles P. Brandt, Daniel J Paulus, Monica Garza, Chad Lemaire, Peter J. Norton, Michael J Zvolensky

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)


Persons living with HIV/AIDS (PLHIV) are able to live full lifespans after infection, however, rates of anxiety disorders among this population are elevated compared to national samples. Importantly, these anxiety symptoms and disorders have a negative effect on medication adherence, quality of life and other psychological disorders, such as depression. In order to reduce the impact of anxiety among PLHIV, a six-session transdiagnostic CBT-based treatment manual for anxiety among PLHIV named the HIV/Anxiety Management-Reduction Treatment (HAMRT) was developed and implemented. The current manuscript discusses the content of this manual as well as results from three cases examining the impact of HAMRT. Results indicated that HAMRT was effective in reducing symptoms of anxiety, anxiety sensitivity, depression, and negative affect among our sample. Additionally, results indicated that HAMRT was effective in increasing HIV medication adherence as well as quality of life. Results are discussed in terms of the potential utility of an anxiety-reduction therapy program aimed at increasing medication adherence among PLHIV.

Original languageEnglish
Pages (from-to)105-118
Number of pages14
JournalCognitive and Behavioral Practice
Issue number1
Publication statusPublished - Feb 2018


  • Anxiety
  • Anxiety sensitivity
  • HIV
  • Medication adherence
  • Negative affect

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