A novel convergent approach to trans-fused polyether frameworks based on the reaction of vinylstannanes and triflates and its application to a synthetic study of the EFGH ring system of gambierol

Chie Kadowaki, Philip W.H. Chan, Isao Kadota, Yoshinori Yamamoto

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)


A new strategy for the convergent assembly of six-membered polycyclic ether ring fragments has been developed based upon the novel reaction between vinylstannanes with triflates in the presence of a strong base. The application of the present method has allowed for a synthetic study of the EFGH ring of gambierol to be achieved. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)5769-5772
Number of pages4
JournalTetrahedron Letters
Issue number30
Publication statusPublished - 22 Jul 2000
Externally publishedYes


  • Coupling
  • Polycyclic ether
  • Triflate
  • Vinylstannane

Cite this