Abstract
Hydrocyanation of a range of protected β-hydroxyalkynes gives unsaturated nitriles which can be cyclised to α-alkylidene γ-lactones and in most cases the regioselectivity of hydrocyanation can be controlled giving the desired cyanoalkenes with stereospecific formation of the E-isomer.
Original language | English |
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Pages (from-to) | 1509-1510 |
Number of pages | 2 |
Journal | Journal of the Chemical Society, Chemical Communications |
Issue number | 21 |
DOIs | |
Publication status | Published - 1 Jan 1985 |