What advantages can GCxGC bring to conventional analysis of drugs? Apart from the recognised improved separation power, and sensitivity, there are new ways to profile drugs. Given the dependence of GC on SIM procedures, where drugs and metabolites (especially for designer drugs) can be overlooked, the higher resolution and sensitivity combined with full mass spectral scanning should improve identification, and permit historical data records to be retro-searched for evidence of presence of previously unsuspected drugs.
|Pages (from-to)||3 - 5|
|Number of pages||3|
|Journal||Chemistry in Australia|
|Publication status||Published - 2007|
Mitrevski, B., Brenna, J., Zhang, Y., & Marriott, P. (2007). A new paradigm in drugs analysis: Comprehensive two-dimensional gas chromatography for steroid analysis. Chemistry in Australia, 74(10), 3 - 5.