TY - JOUR
T1 - A new paradigm in drugs analysis: Comprehensive two-dimensional gas chromatography for steroid analysis
AU - Mitrevski, Blagoj
AU - Brenna, J
AU - Zhang, Y
AU - Marriott, Philip
PY - 2007
Y1 - 2007
N2 - What advantages can GCxGC bring to conventional analysis of drugs? Apart from the recognised improved separation power, and sensitivity, there are new ways to profile drugs. Given the dependence of GC on SIM procedures, where drugs and metabolites (especially for designer drugs) can be overlooked, the higher resolution and sensitivity combined with full mass spectral scanning should improve identification, and permit historical data records to be retro-searched for evidence of presence of previously unsuspected drugs.
AB - What advantages can GCxGC bring to conventional analysis of drugs? Apart from the recognised improved separation power, and sensitivity, there are new ways to profile drugs. Given the dependence of GC on SIM procedures, where drugs and metabolites (especially for designer drugs) can be overlooked, the higher resolution and sensitivity combined with full mass spectral scanning should improve identification, and permit historical data records to be retro-searched for evidence of presence of previously unsuspected drugs.
UR - http://search.informit.com.au/fullText;dn=838501746337762;res=IELENG
M3 - Article
SN - 0314-4240
VL - 74
SP - 3
EP - 5
JO - Chemistry in Australia
JF - Chemistry in Australia
IS - 10
ER -