A new mechanistic pathway under Sonogashira reaction protocol involving multiple acetylene insertions

Roderick C Jones; Allan J Canty; Tom Caradoc-Davies; Noel W Davies; Michael G Gardiner; Philip Marriott; Christian P G Ruhle; Vicki -Anne Tolhurst

doi:10.1039/c001109f

A new mechanistic pathway under Sonogashira reaction protocol involving multiple acetylene insertions

Roderick C Jones
, Allan J Canty
, Tom Caradoc-Davies
, Noel W Davies
, Michael G Gardiner
, Philip Marriott
, Christian P G Ruhle
, Vicki -Anne Tolhurst

Research output: Contribution to journal › Article › Research › peer-review

9 Citations (Scopus)

Abstract

An unreported product outcome from an intended Sonogashira coupling is presented. The generality of this finding has been demonstrated by screening of a range of precatalysts. Mechanistic studies are consistent with the tetraaryl benzene product forming by interception of the aryl halide oxidative addition intermediate by repeated acetylene insertion.

Original language	English
Pages (from-to)	3799 - 3801
Number of pages	3
Journal	Dalton Transactions
Volume	39
Issue number	16
DOIs	https://doi.org/10.1039/c001109f
Publication status	Published - 2010
Externally published	Yes

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10.1039/c001109f

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title = "A new mechanistic pathway under Sonogashira reaction protocol involving multiple acetylene insertions",

abstract = "An unreported product outcome from an intended Sonogashira coupling is presented. The generality of this finding has been demonstrated by screening of a range of precatalysts. Mechanistic studies are consistent with the tetraaryl benzene product forming by interception of the aryl halide oxidative addition intermediate by repeated acetylene insertion.",

author = "Jones, \{Roderick C\} and Canty, \{Allan J\} and Tom Caradoc-Davies and Davies, \{Noel W\} and Gardiner, \{Michael G\} and Philip Marriott and Ruhle, \{Christian P G\} and Tolhurst, \{Vicki -Anne\}",

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AU - Jones, Roderick C

AU - Canty, Allan J

AU - Caradoc-Davies, Tom

AU - Davies, Noel W

AU - Gardiner, Michael G

AU - Marriott, Philip

AU - Ruhle, Christian P G

AU - Tolhurst, Vicki -Anne

PY - 2010

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AB - An unreported product outcome from an intended Sonogashira coupling is presented. The generality of this finding has been demonstrated by screening of a range of precatalysts. Mechanistic studies are consistent with the tetraaryl benzene product forming by interception of the aryl halide oxidative addition intermediate by repeated acetylene insertion.

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VL - 39

SP - 3799

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JO - Dalton Transactions

JF - Dalton Transactions

IS - 16

ER -

A new mechanistic pathway under Sonogashira reaction protocol involving multiple acetylene insertions

Abstract

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