A new bis-labdanic diterpene from the rhizomes of alpinia pahangensis

Khalijah Awang; Yasodha Sivasothy; Halijah Ibrahim; Audra Shaleena Paliany; Siti Aisyah Alias; Nurur Raudzah Md Nor

doi:10.1055/s-0033-1351075

A new bis-labdanic diterpene from the rhizomes of alpinia pahangensis

Khalijah Awang, Yasodha Sivasothy, Halijah Ibrahim, Audra Shaleena Paliany, Siti Aisyah Alias, Nurur Raudzah Md Nor

Research output: Contribution to journal › Article › Research › peer-review

11 Citations (Scopus)

Abstract

The rhizomes of Alpinia pahangensis yielded a new bis-labdanic diterpene for which the name pahangensin C (1) was proposed along with twelve known analogues (2-13). The structure of 1 was elucidated via spectroscopic methods including 1D and 2D NMR techniques and LCMS-IT-TOF analysis. Compounds 2 and 12 were isolated for the first time from the genus Alpinia. This is the second occurrence of compounds 2 and 12 in the Zingiberaceae family. Selected analogues exhibited moderate to strong inhibitory activity against Staphylococcus aureus and Bacillus cereus.

Original language	English
Pages (from-to)	1775-1780
Number of pages	6
Journal	Planta Medica
Volume	79
Issue number	18
DOIs	https://doi.org/10.1055/s-0033-1351075
Publication status	Published - Dec 2013
Externally published	Yes

Keywords

Alpinia pahangensis
bis-labdanic diterpene
labdane diterpene
pahangensin C
Zingiberaceae

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10.1055/s-0033-1351075

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abstract = "The rhizomes of Alpinia pahangensis yielded a new bis-labdanic diterpene for which the name pahangensin C (1) was proposed along with twelve known analogues (2-13). The structure of 1 was elucidated via spectroscopic methods including 1D and 2D NMR techniques and LCMS-IT-TOF analysis. Compounds 2 and 12 were isolated for the first time from the genus Alpinia. This is the second occurrence of compounds 2 and 12 in the Zingiberaceae family. Selected analogues exhibited moderate to strong inhibitory activity against Staphylococcus aureus and Bacillus cereus.",

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T1 - A new bis-labdanic diterpene from the rhizomes of alpinia pahangensis

AU - Awang, Khalijah

AU - Sivasothy, Yasodha

AU - Ibrahim, Halijah

AU - Paliany, Audra Shaleena

AU - Alias, Siti Aisyah

AU - Md Nor, Nurur Raudzah

PY - 2013/12

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AB - The rhizomes of Alpinia pahangensis yielded a new bis-labdanic diterpene for which the name pahangensin C (1) was proposed along with twelve known analogues (2-13). The structure of 1 was elucidated via spectroscopic methods including 1D and 2D NMR techniques and LCMS-IT-TOF analysis. Compounds 2 and 12 were isolated for the first time from the genus Alpinia. This is the second occurrence of compounds 2 and 12 in the Zingiberaceae family. Selected analogues exhibited moderate to strong inhibitory activity against Staphylococcus aureus and Bacillus cereus.

KW - Alpinia pahangensis

KW - bis-labdanic diterpene

KW - labdane diterpene

KW - pahangensin C

KW - Zingiberaceae

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SN - 0032-0943

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JO - Planta Medica

JF - Planta Medica

IS - 18

ER -

A new bis-labdanic diterpene from the rhizomes of alpinia pahangensis

Abstract

Keywords

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