A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides

Michelle Ma; John Karas; Jonathan White; Denis Scanlon; Paul Donnelly

doi:10.1039/b903426a

A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides

Michelle Ma, John Karas, Jonathan White, Denis Scanlon, Paul Donnelly

Research output: Contribution to journal › Article › Research › peer-review

54 Citations (Scopus)

Abstract

A new sarcophagine cage amine ligand with a pendent carboxylate functional group has been synthesised; the ligand has been conjugated to tumour targeting peptides ([Tyr(3)]-octreotate and [Lys(3)]-bombesin) and the conjugates radiolabelled with copper-64.

Original language	English
Pages (from-to)	3237 - 3239
Number of pages	3
Journal	Chemical Communications
DOIs	https://doi.org/10.1039/b903426a
Publication status	Published - 2009
Externally published	Yes

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10.1039/b903426a

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title = "A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides",

abstract = "A new sarcophagine cage amine ligand with a pendent carboxylate functional group has been synthesised; the ligand has been conjugated to tumour targeting peptides ([Tyr(3)]-octreotate and [Lys(3)]-bombesin) and the conjugates radiolabelled with copper-64.",

author = "Michelle Ma and John Karas and Jonathan White and Denis Scanlon and Paul Donnelly",

year = "2009",

doi = "10.1039/b903426a",

language = "English",

pages = "3237 -- 3239",

journal = "Chemical Communications",

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publisher = "The Royal Society of Chemistry",

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T1 - A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides

AU - Ma, Michelle

AU - Karas, John

AU - White, Jonathan

AU - Scanlon, Denis

AU - Donnelly, Paul

PY - 2009

Y1 - 2009

N2 - A new sarcophagine cage amine ligand with a pendent carboxylate functional group has been synthesised; the ligand has been conjugated to tumour targeting peptides ([Tyr(3)]-octreotate and [Lys(3)]-bombesin) and the conjugates radiolabelled with copper-64.

AB - A new sarcophagine cage amine ligand with a pendent carboxylate functional group has been synthesised; the ligand has been conjugated to tumour targeting peptides ([Tyr(3)]-octreotate and [Lys(3)]-bombesin) and the conjugates radiolabelled with copper-64.

UR - http://pubs.rsc.org.ezproxy.lib.monash.edu.au/en/content/articlepdf/2009/cc/b903426a

U2 - 10.1039/b903426a

DO - 10.1039/b903426a

M3 - Article

SN - 1359-7345

SP - 3237

EP - 3239

JO - Chemical Communications

JF - Chemical Communications

ER -

A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides

Abstract

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