A new asymmetric synthesis of (+)-grandisol via a kinetic resolution

David P G Hamon; Kellie L. Tuck

doi:10.1016/S0040-4039(99)01605-6

A new asymmetric synthesis of (+)-grandisol via a kinetic resolution

David P G Hamon, Kellie L. Tuck

Research output: Contribution to journal › Article › Research › peer-review

10 Citations (Scopus)

Abstract

A novel approach to the asymmetric synthesis of (+)-grandisol involves the use of catalytic kinetic resolution of a primary allylic alcohol. The allylic alcohol is prepared in 4 steps from simple achiral materials and the resolved alcohol (95%e.e.) is reduced in 2 steps to the corresponding methyl alkene. This alkene is converted to (+)-grandisol (95%e.e.).

Original language	English
Pages (from-to)	7569-7572
Number of pages	4
Journal	Tetrahedron Letters
Volume	40
Issue number	42
DOIs	https://doi.org/10.1016/S0040-4039(99)01605-6
Publication status	Published - 15 Oct 1999
Externally published	Yes

Access to Document

10.1016/S0040-4039(99)01605-6

Cite this

@article{f63058f2e16e40fea3c73d7dba625c44,

title = "A new asymmetric synthesis of (+)-grandisol via a kinetic resolution",

abstract = "A novel approach to the asymmetric synthesis of (+)-grandisol involves the use of catalytic kinetic resolution of a primary allylic alcohol. The allylic alcohol is prepared in 4 steps from simple achiral materials and the resolved alcohol (95%e.e.) is reduced in 2 steps to the corresponding methyl alkene. This alkene is converted to (+)-grandisol (95%e.e.).",

author = "Hamon, {David P G} and Tuck, {Kellie L.}",

year = "1999",

month = oct,

day = "15",

doi = "10.1016/S0040-4039(99)01605-6",

language = "English",

volume = "40",

pages = "7569--7572",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier",

number = "42",

}

TY - JOUR

T1 - A new asymmetric synthesis of (+)-grandisol via a kinetic resolution

AU - Hamon, David P G

AU - Tuck, Kellie L.

PY - 1999/10/15

Y1 - 1999/10/15

N2 - A novel approach to the asymmetric synthesis of (+)-grandisol involves the use of catalytic kinetic resolution of a primary allylic alcohol. The allylic alcohol is prepared in 4 steps from simple achiral materials and the resolved alcohol (95%e.e.) is reduced in 2 steps to the corresponding methyl alkene. This alkene is converted to (+)-grandisol (95%e.e.).

AB - A novel approach to the asymmetric synthesis of (+)-grandisol involves the use of catalytic kinetic resolution of a primary allylic alcohol. The allylic alcohol is prepared in 4 steps from simple achiral materials and the resolved alcohol (95%e.e.) is reduced in 2 steps to the corresponding methyl alkene. This alkene is converted to (+)-grandisol (95%e.e.).

UR - http://www.scopus.com/inward/record.url?scp=0033570047&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(99)01605-6

DO - 10.1016/S0040-4039(99)01605-6

M3 - Article

AN - SCOPUS:0033570047

SN - 0040-4039

VL - 40

SP - 7569

EP - 7572

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 42

ER -

A new asymmetric synthesis of (+)-grandisol via a kinetic resolution

Abstract

Access to Document

Other files and links

Cite this