A naturally shaped silicone ventricle evaluated in a mock circulation loop: A preliminary study

S. Gregory, D. Timms, M. J. Pearcy, G. Tansley

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12 Citations (Scopus)


Mock circulation loops are used to evaluate the performance of cardiac assist devices prior to animal and clinical testing. A compressible, translucent silicone ventricle chamber that mimics the exact size, shape and motion of a failing heart is desired to assist in flow visualization studies around inflow cannulae during VAD support. The aim of this study was therefore to design and construct a naturally shaped flexible left ventricle and evaluate its performance in a mock circulation loop. The ventricle shape was constructed by the use of CT images taken from a patient experiencing cardiomyopathic heart failure and used to create a 3D image and subsequent mould to produce a silicone ventricle. Different cardiac conditions were successfully simulated to validate the ventricle performance, including rest, left heart failure and VAD support.

Original languageEnglish
Pages (from-to)185-191
Number of pages7
JournalJournal of Medical Engineering and Technology
Issue number3
Publication statusPublished - 1 Apr 2009
Externally publishedYes


  • Mock circulation loop
  • Silicone ventricle
  • Ventricular assist device

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