A microwave assisted intramolecular-furan-Diels-Alder approach to 4-substituted indoles

Filip Petronijevic; Cody Timmons; Anthony Cuzzupe; Peter Wipf

doi:10.1039/b816989f

A microwave assisted intramolecular-furan-Diels-Alder approach to 4-substituted indoles

Filip Petronijevic, Cody Timmons, Anthony Cuzzupe, Peter Wipf

Research output: Contribution to journal › Article › Research › peer-review

52 Citations (Scopus)

Abstract

The key steps of a versatile new protocol for the convergent synthesis of 3,4-disubstituted indoles are the addition of an α-lithiated alkylaminofuran to a carbonyl compound, a microwave-accelerated intramolecular Diels-Alder cycloaddition and an in situ double aromatization reaction.

Original language	English
Pages (from-to)	104-106
Number of pages	3
Journal	Chemical Communications
Issue number	1
DOIs	https://doi.org/10.1039/b816989f
Publication status	Published - 2009
Externally published	Yes

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abstract = "The key steps of a versatile new protocol for the convergent synthesis of 3,4-disubstituted indoles are the addition of an α-lithiated alkylaminofuran to a carbonyl compound, a microwave-accelerated intramolecular Diels-Alder cycloaddition and an in situ double aromatization reaction.",

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AB - The key steps of a versatile new protocol for the convergent synthesis of 3,4-disubstituted indoles are the addition of an α-lithiated alkylaminofuran to a carbonyl compound, a microwave-accelerated intramolecular Diels-Alder cycloaddition and an in situ double aromatization reaction.

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A microwave assisted intramolecular-furan-Diels-Alder approach to 4-substituted indoles

Abstract

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