A metal-containing NP approach to treat methicillin-resistant Staphylococcus aureus (MRSA): Prospects and challenges

Wendy Wai Yeng Yeo, Sathiya Maran, Amanda Shen-Yee Kong, Wan-Hee Cheng, Swee-Hua Erin Lim, Jiun-Yan Loh, Kok-Song Lai

Research output: Contribution to journalReview ArticleResearchpeer-review

6 Citations (Scopus)

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of pneumonia in humans, and it is associated with high morbidity and mortality rates, especially in immunocompromised patients. Its high rate of multidrug resistance led to an exploration of novel antimicrobials. Metal nanoparticles have shown potent antibacterial activity, thus instigating their application in MRSA. This review summarizes current insights of Metal-Containing NPs in treating MRSA. This review also provides an in-depth appraisal of opportunities and challenges in utilizing metal-NPs to treat MRSA.

Original languageEnglish
Article number5802
Number of pages14
JournalMaterials
Volume15
Issue number17
DOIs
Publication statusPublished - 1 Sept 2022

Keywords

  • antibacterial-resistance
  • bacteria
  • biomedical applications
  • metals
  • NP
  • Staphylococcus aureus

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