A longitudinal study of thyroid autoantibodies in pregnancy: the importance of test timing

Elif I Ekinci, Wei-Ling Chiu, Zhong Xian Lu, Ken Andrew Sikaris, Leonid Churilov, Intissar Bittar, Que Lam, Nick Crinis, Christine A Houlihan

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27 Citations (Scopus)

Abstract

OBJECTIVE: Thyroid peroxidase antibodies (TPOAb) and thyroglobulin antibodies (TGAb) are frequently measured to investigate thyroid dysfunction in pregnancy. Despite the recognized fall of these autoantibodies in pregnancy, there is limited guidance on the timing of such testing. We assessed optimal test timing of TPOAb/TGAb for the detection of Hashimoto s thyroiditis and post-partum thyroid dysfunction (PPTD). DESIGN: Prospective longitudinal study with recruitment in Trimester 1. PATIENTS: Healthy women
Original languageEnglish
Pages (from-to)604 - 610
Number of pages7
JournalClinical Endocrinology
Volume82
Issue number4
DOIs
Publication statusPublished - 2015

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