A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency

Soesma A. Jankipersadsing; Fatemeh Hadizadeh; Marc Jan Bonder; Ettje F. Tigchelaar; Patrick Deelen; Jingyuan Fu; Anna Andreasson; Lars Agreus; Susanna Walter; Cisca Wijmenga; Pirro Hysi; Mauro D'Amato; Alexandra Zhernakova

doi:10.1136/gutjnl-2016-312398

A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency

Soesma A. Jankipersadsing, Fatemeh Hadizadeh, Marc Jan Bonder, Ettje F. Tigchelaar, Patrick Deelen, Jingyuan Fu, Anna Andreasson, Lars Agreus, Susanna Walter, Cisca Wijmenga, Pirro Hysi, Mauro D'Amato, Alexandra Zhernakova

Research output: Contribution to journal › Letter › Other › peer-review

16 Citations (Scopus)

Abstract

Stool consistency and frequency patterns are complex traits that are often altered in GI disease, and recent studies published in Gut highlight the importance of stool frequency in relation to gut microbiota composition and the efficacy of pharmacological and dietary treatments in IBS.

Original language	English
Pages (from-to)	756-758
Number of pages	3
Journal	Gut
Volume	66
Issue number	4
DOIs	https://doi.org/10.1136/gutjnl-2016-312398
Publication status	Published - 1 Apr 2017
Externally published	Yes

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Jankipersadsing, S. A., Hadizadeh, F., Bonder, M. J., Tigchelaar, E. F., Deelen, P., Fu, J., Andreasson, A., Agreus, L., Walter, S., Wijmenga, C., Hysi, P., D'Amato, M., & Zhernakova, A. (2017). A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency. Gut, 66(4), 756-758. https://doi.org/10.1136/gutjnl-2016-312398

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abstract = "Stool consistency and frequency patterns are complex traits that are often altered in GI disease, and recent studies published in Gut highlight the importance of stool frequency in relation to gut microbiota composition and the efficacy of pharmacological and dietary treatments in IBS.",

author = "Jankipersadsing, {Soesma A.} and Fatemeh Hadizadeh and Bonder, {Marc Jan} and Tigchelaar, {Ettje F.} and Patrick Deelen and Jingyuan Fu and Anna Andreasson and Lars Agreus and Susanna Walter and Cisca Wijmenga and Pirro Hysi and Mauro D'Amato and Alexandra Zhernakova",

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doi = "10.1136/gutjnl-2016-312398",

language = "English",

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Jankipersadsing, SA, Hadizadeh, F, Bonder, MJ, Tigchelaar, EF, Deelen, P, Fu, J, Andreasson, A, Agreus, L, Walter, S, Wijmenga, C, Hysi, P, D'Amato, M & Zhernakova, A 2017, 'A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency', Gut, vol. 66, no. 4, pp. 756-758. https://doi.org/10.1136/gutjnl-2016-312398

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T1 - A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency

AU - Jankipersadsing, Soesma A.

AU - Hadizadeh, Fatemeh

AU - Bonder, Marc Jan

AU - Tigchelaar, Ettje F.

AU - Deelen, Patrick

AU - Fu, Jingyuan

AU - Andreasson, Anna

AU - Agreus, Lars

AU - Walter, Susanna

AU - Wijmenga, Cisca

AU - Hysi, Pirro

AU - D'Amato, Mauro

AU - Zhernakova, Alexandra

PY - 2017/4/1

Y1 - 2017/4/1

N2 - Stool consistency and frequency patterns are complex traits that are often altered in GI disease, and recent studies published in Gut highlight the importance of stool frequency in relation to gut microbiota composition and the efficacy of pharmacological and dietary treatments in IBS.

AB - Stool consistency and frequency patterns are complex traits that are often altered in GI disease, and recent studies published in Gut highlight the importance of stool frequency in relation to gut microbiota composition and the efficacy of pharmacological and dietary treatments in IBS.

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U2 - 10.1136/gutjnl-2016-312398

DO - 10.1136/gutjnl-2016-312398

M3 - Letter

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AN - SCOPUS:84979701315

SN - 0017-5749

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SP - 756

EP - 758

JO - Gut

JF - Gut

IS - 4

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A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency

Abstract

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